Primary faculty
Research interests: Cancer cell heterogeneity and plasticity; cancer stem cells; stem cells; epigenetics; noncoding RNAs; prostate cancer
Research interests: Deubiquitinating and chromatin-modifying enzymes in cancer development and progression.
Research interests: Microenvironmental regulation of extracellular matrix proteins promoting cancer progression and tissue healing aspects of regenerative medicine
Research interests: Mitochondrial unfolded protein response and cancer health disparities
Research interests: Exploiting crosstalk between estrogen receptors and p53 (wild type and mutant) signaling for developing novel therapeutic strategies against cancer
Research interests: Dissect epigenetic mechanisms that regulate physiological and pathological processes and translate them into therapeutics
Research interests: Gene regulation, GPCR signaling, and therapeutic development in pancreatic cancer
Research interests: Preclinical testing of novel therapeutics using in vivo model systems with a focus in prostate and bladder cancer
Research interests: Understanding how tumor suppressor gene regulated molecular pathways influence cancer progression and therapeutic resistance
Research interests: Anticancer drug discovery, development and mechanism of action (MOA) studies; IND-enabling studies
Research Interests: small RNAs, RNA binding proteins, RNA therapeutics, circulating RNAs, metastasis
Research interests: MDM2, MDM4, Small molecule inhibitor, Cell death, Cell cycle
Research interests: Genetic and epigenetic drivers of urological malignancies
Research faculty - Assistant Professors of Oncology
Research interests: Prostate cancer biology, Mitochondrial UPR and Metabolism, Drug Target Discovery, lncRNA, Genomic Instability
Research interests: To understand and prevent prostate cancer castration resistance
Research interests: Establishment, characterization, and utilization of pre-clinical in vivo models for basic and translational cancer research
Joint appointment
Research interests: Therapeutically targeting prostate cancer and BPH stem cells ABC transporter regulation of stem cell properties Role of cancer stem cells in tumor heterogeneity
Research interests: Develop preclinical bladder cancer models (genetic engineered mouse models and patient-derived organoids), identify biomarkers associated with treatment responses, and improve chemotherapy efficacy by inhibiting the nucleotide excision repair pathway
Research Interests: DNA damage repair, tumor microenvironment signaling, and antiestrogen therapy in ovarian cancer
Research interests: Multi-omics analysis and integration to better understand dysregulated tumor, microenvironment and immune metabolism
Research interests: Vascular biology of head and neck cancers Chemoprevention of oral cancer Multimodal imaging (CT, US, Photoacoustic imaging)
Research interests: Mechanism of differentiation responses and resistance to FLT3 targeted therapy in AML