Welcome to The Department of Cell Stress Biology.
The department is comprised of 12 major research laboratory units located in close proximity to each other on the campus of Roswell Park Cancer Institute. The Department is also closely associated with the Small Molecule Core and PDT Center. The investigators of the Department also represent the core faculty of the Biophysical Therapies Program, an important component of the National Cancer Institute Cancer Center Support Grant (CCSG) awarded to Roswell Park Cancer Institute. A number of adjunct faculty members provide important links to other departments, such as Cancer Genetics and Genomics and Immunology.
The Small Molecule Screening Core (SMSC) Facility provides investigators with the possibility of screening chemical libraries in a variety of readout systems for new prospective diagnostic and therapeutic compounds and research tools.
Photodynamic therapy (PDT) was developed at RPCI, and the PDT Center is a worldwide leader in its use for treating many types of cancer. PDT, developed in the late 1970s by Thomas Dougherty, PhD, Chief Emeritus of the Center, is a targeted anticancer treatment — one that kills tumor cells without permanently damaging surrounding tissue.