Dermatopathology Division

Offering providers fast, accurate pathologic diagnosis of cancer and nonmalignant skin diseases.

This site is intended for healthcare professionals.

Our subspecialty pathology laboratory — backed by the expertise of the region’s only National Cancer Institute-designated comprehensive cancer center — offers critical dermatopathology diagnosis for all dermatologic conditions.

Account loginRequisitions, forms & documentsMeet the team

What sets us apart

You and your patients need a timely and reliable diagnosis so appropriate treatment and relief can begin promptly. We offer:

  • Academic diagnostic expertise in melanoma, cutaneous lymphoma, other skin tumors, rashes and difficult pigmented lesions
  • Customer service of a local, community-based laboratory
  • Direct access to our dermatopathologists
  • Primary diagnosis and second opinion consultations
  • Comprehensive participation with local insurance companies
  • Multiple options for report delivery, including integration with EMRs, WNY Healthelink, and a secure physician report portal available from any web browser

To get started or for more information:

Fill out this form and we will contact you to help set up your account or answer your questions; you can also call us directly at 716-845-4510.

How it works

RPCI Laboratories is dedicated to providing accurate diagnosis with exceptional turnaround time. Routine cases are typically completed and reported one to two business days after the specimen is received at the laboratory. Second opinion consultation cases, because of their complex nature and the occasional need for additional testing, may take longer to result.

To get started submitting new specimens, please contact our laboratory using the web form above. Our team will reach out to discuss your needs and establish an account for your practice. We arrange courier pick-up of the cases at a frequency you choose and establish a report delivery mechanism that integrates with your clinical workflow.

The dermatopathologists of RPCI Laboratories also do second opinion consultations for our colleagues in pathology and dermatology. During the second opinion evaluation, we review the original laboratory's slide material and correlate our findings with any existing pathology reports and the available clinical history. Sometimes additional testing of the material can be useful or necessary to ensure accurate diagnosis. If that is the case, we may request additional unstained slides or a paraffin block to facilitate the work-up, but we are always mindful of the cost of care and strive for efficient and accurate diagnosis.

Download the pathology specimen collection guide Download

Proper specimen handling requires that specimen integrity be maintained by proper preservative (where required), and that the sample identification and patient identification is clearly labeled on the specimen container and test requisition. The information listed below is to assist with that objective.

  1. Provide general information

    All histology specimens received by the laboratory must be accompanied by a completed surgical pathology requisition which includes the following information:

    Correct patient sample labeling is confirmed by comparing all information listed on the specimen container to information written on the requisition and information verbalized by patient or responsible party (if minor or unable to do so).

    Verbal verification of the source, nature, number of specimens and appropriate container/preservative occurs between physician and nursing staff prior to delivery of the specimen to the laboratory.

    • Patient’s full name
    • Patient’s Date of Birth
    • Patient’s gender
    • Insurance information/Billing information
    • Photocopyofpatient’sinsurancecard(front and back)
    • Physician(s) name
    • Date and time of specimen collection
    • Source of specimen (anatomic site)
    • Briefclinicalhistory/pre-operative diagnosis (ICD-10 code; CLIA requirement)
  2. Label specimen containers

    Specimen containers are not pre-labeled, but instead are labeled immediately after the specimen is placed into the container.

    • Specimen containers are labeled with the patient’s complete name, a second patient identifier, date of birth, and specimen (anatomic) site.
    • Specimens are labeled with patient identification on the bottle, not on the cap. Multiple specimens are placed in individual bottles.
    • The surgical specimen is properly identified by listing WHAT the specimens (skin, mass, tumor, etc.) and WHERE (anatomical site) it was obtained. Include whether the specimen is from a RIGHT or LEFT anatomical site.
    • A review of the completeness and accuracy of the requisition in comparison with the labeling of the specimen container and patient occurs prior to leaving the procedural site.
  3. Please follow specimen requirements

    Most specimens (but not all) are preserved and delivered to the lab in 10% formalin to avoid cellular degeneration. Formalin volume should be 20% greater than the specimen. Place the sample in a biohazard bag. One patient per bag; multiple samples from one patient can be placed in the same bag. Requisition form to be placed in the outside pocket of the biohazard bag.

Download the pathology specimen transport guide Download

Proper specimen handling requires that specimen integrity be maintained by proper preservative and that the sample identification and patient identification is clearly labeled on the specimen container and test requisition.

  1. Please follow specimen requirements

    Most specimens are preserved and delivered to the lab in 10% formalin to avoid cellular degeneration. Formalin volume should be 20% greater than the specimen. It is imperative that the bottles are securely closed to avoid leaks and dried out samples.

  2. Forms
    • Courier Log for Clients: This form is for your reference and for your office to keep (for possible discrepancies with sample delivery)
    • Delivery Form: Complete the “Delivery Form” with only the patients last name, date and number of containers.
  3. Courier Package

    Place the patient biohazard specimen bags/patient requisition into a paper bag for courier pick up. Use the U-secure tamper evident tape to seal paper bag. Attach completed “Delivery form” to outside of paper bag.

  4. Courier Pick Up

    Call Foxy at 1-716-876-3828 to schedule pick up. Have a courier initial the Courier Log. For more distant clinical offices, national courier pick up (such as FedEx) can be arranged.

When participating with the patient’s insurance, we will submit a claim directly to insurance.  For direct costs of consultation, please call our laboratory to discuss.

To submit a case for review, please have the original laboratory forward (by registered courier) the following items to RPCI Laboratories at 6420 Transit Road, Depew, NY 14701:

  1. A completed second opinion requisition (download requisition)
  2. A copy of the original specimen requisition
  3. A copy of the original pathology report (final or preliminary) for the case
  4. Patient demographic and insurance information
  5. Any relevant clinical images or history that could be helpful diagnostically
  6. All available case glass slides
  7. If the case may benefit from additional testing, please feel free to forward additional unstained slides or paraffin blocks to expedite our evaluation.

RPCI Laboratories has a comprehensive insurance participation, and we are always working to add additional options. Please check back as this list will continue to expand.

Insurance accepted

  • Emblem Health
  • Fidelis Care, including Wellcare Medicare
  • Highmark BCBS WNY
  • Independent Health
  • Magnacare Network including self-funded AETNA (not Medicare), Brighton, Coventry First Health
  • Martin’s Point, through US Family Health Plan
  • Medicare
  • Molina/Monroe Plan (formerly YourCare)
  • Multiplan Network/PHCS
  • MVP Health Plan, including self-funded CIGNA w/MVP logo on card
  • NYS Empire Plan
  • NYS Medicaid
  • Nova Healthcare
  • United Healthcare/UMR/AARP
  • Univera/EBS-RMSCO/Lifetime Benefit Solutions
  • UPMC (Jamestown & CMP providers only)
  • Wellcare (CMP providers only)

Download requisitions, forms & procedure documents

Requisitions, forms and documents

Supply order form

NOTE: Supplies can also be ordered using the Lifepoint web portal


Blank dematopathology specimen requisition


Second opinion requisition


Courier delivery manifest