The overall mission of Roswell Park's Translational Imaging Shared Resource (TISR) is to provide specialized services relating to the imaging of small animal models of disease. The Resource provides scientific and technical services pertaining to image acquisition, quantitative image analysis, multidimensional renderings and visualization of imaging data sets for research. The objective of TISR is to facilitate the conduct and progress of scientific research at Roswell Park by:
- Providing the necessary intellectual and physical resources relating to non-invasive in vivo imaging
- Developing novel preclinical imaging techniques that provide insight into various biological processes involved in cancer and enable the conduct of preclinical trials of experimental therapeutics in animal models
- Establishing a technology platform that would allow translation of imaging techniques evaluated in preclinical models to improve disease detection and monitoring of therapeutic response in the clinical arena
TISR offers customized services to investigators relating to the use of state-of-the-art small animal imaging techniques including magnetic resonance imaging (MRI) and spectroscopy (MRS), fluorescent protein imaging and multispectral imaging. The Resource has recently expanded to include ultrasound (US), bioluminescence, photoacoustic, and x-ray imaging services.
Translational Imaging Shared Resource
Roswell Park Comprehensive Cancer Center
Cancer Cell Center, Room 164
Elm and Carlton Streets
Buffalo, New York 14263
Monday – Friday, 8 a.m. – 5 p.m.
TISR provides 24/7 access to and training in non-invasive imaging technologies to Cancer Center Support Grant (CCSG) members in a cost-effective manner.
Core Grant Citation
This resource is funded by the RPCI Cancer Center Support Grant (CCSG) awarded by the National Cancer Institute (NCI P30CA16056). Publications that have utilized facility resources, services or scientific data generated by the resource should acknowledge the resource or the assistance provided by resource staff and cite the NCI CCSG grant. An electronic copy of the publication should also be sent to the resource directors.
The work utilized resources and services provided by the Translational Imaging Shared Resource at Roswell Park are supported by NCI P30CA16056. The authors would also like to acknowledge the resource staff for their technical assistance in performing the imaging studies.