Harnessing RNA to fight cancer: From mechanisms to therapeutics
The Liu Lab is discovering key post-transcriptional mechanisms that govern metastasis and translating these insights into novel therapeutic strategies:
- Mechanisms underlying 5’ UTR-mediated transcript regulation
- Targeting a pro-metastatic RNA-protein complex in breast cancer metastasis
- Developing next-generation RNA therapeutics for cancer treatments
We employ a multidisciplinary approach that combines cutting-edge genomics and proteomics techniques, advanced bioinformatic analyses, in vivo mouse models, in vitro patient-derived xenograft organoids, and classical molecular biology and biochemistry.
Lab Research
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Postdoctoral fellows in non-coding RNA, RNA therapeutics and breast cancer research
Faculty affiliations
Contact Information
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Department of Pharmacology and Therapeutics
Roswell Park Comprehensive Cancer Center
Elm and Carlton Streets
Buffalo, NY 14263