Roswell Park’s education programs support all forms of training in cancer research including summer internships, PhD programs, and Postdoctoral mentoring.
Pre-Doc mentoring
Ethan Abel, PhD
Our lab is interested in examining the interplay between oncogenic signaling pathways and transcription factors in pancreatic cancer. In particular, we are interested in how these converging factors control therapeutic resistance, tumorigenesis, cancer stem cells, and cell lineage identity/plasticity.
For example, much of our research examines the roles of the endodermal-lineage transcription factor HNF1A, including its role as a driver of the pancreatic cancer stem cell state and its interactions with mutant KRAS, the primary oncogene in pancreatic cancer.
Our lab combines mechanistic cell and molecular biology with translational approaches (e.g., experimental therapeutics and patient-derived xenografts) to identify novel drivers of, and potential therapeutic targets for the disease.
Current students
- Katherine Crawford
- Kennedy Humphrey
Erik Knudsen, PhD
Our lab has studied cell cycle regulatory pathways and the retinoblastoma tumor suppressor for 25 years.
Multiple graduate students have been trained in the laboratory who have gone on to have successful careers including as tenure-track faculty, pharmaceutical scientists, NCI administrators, and even a hedge-fund manager.
The lab is highly dynamic and we enjoy having students in the group.
Current students
- Karissa Bonis
- Adam Dommer
- Subrahmanya Anirudh Kaligotla Venkata
- Yin Wan
Hai Wang, PhD
The Wang Lab investigates biological mechanisms and therapeutic strategies to target bone metastasis in breast cancer and prostate cancer. Our research primarily focuses on the role of metabolic reprogramming in bone metastases.
Current students
- Cheyenne Ernst
Post-Doctoral appointments/mentoring
Joseph Lau, PhD
We are searching for an ambitious PhD, MD, or PhD-MD biologist for a postdoctoral research project for the identification and functional analysis of novel glycan-based cell-niche interactions in blood cell production and function.
Projects will be oriented around one or some combinations of the following topics:
- Identification and characterization of novel cell-niche in maintenance of hematopoietic stem cells
- The study of disruption to healthy hematopoiesis by normal cells neighboring malignant and pre-malignant neoplasms; role of glycans in the tumor and cancer stem cell niche.
The research environment is highly interactive; the laboratory is part of a multisite NIH funded K12 Training Program of Excellence in Glycosciences geared toward mentorship and development of the next generation translational glycoscientists.
Current students
- Ogechi Ogoke
- Tin Long Wong
Hai Wang, PhD
The Wang lab focuses on studying the molecular basis that underlines tumor-microenvironment interaction in bone and other metastases of breast and prostate cancer. The postdoctoral position is focused on understanding the metabolic reprograming of cancer cells in bone metastases as novel therapeutic targets. Studies will involve multiple different approaches to study tumor biology in cell and animal models, complemented by the use of genomic and metabolomic approaches. Postdoctoral fellows will be expected to direct independent projects in a multi-disciplinary setting. Multidisciplinary training in molecular biology, cellular biology and various mouse model systems including xenograft, syngeneic and transgenic mice will be offered.
Current students
- Renuka Dahiya, PhD
Questions?
Jennifer Panaro
Scientific Department Administrator ll
Phone: 716-845-1300, x1929
Email: Jennifer.Panaro@RoswellPark.org