The role of the nervous system in regulating cellular stress responses
Inside the lab of Veena Prahlad, PhD, MSc, we investigate how organisms adapt to suboptimal conditions. Currently we are investigating how the nervous system of a multicellular animal controls and responds to stress response programs activated by its cells and tissues.
We also explore how neuronal signals impact the age-related dysregulation of stress response pathways in neurodegenerative diseases and cancer.
Understanding how organisms respond to biotic and abiotic stressors
How do cells within a multicellular organism respond to damage to their macromolecules? Is each cell ‘allowed’ to respond as and when it needs to, prioritizing its survival and defense over community activities in the tissue? Or are there rules arising from intercellular interactions that determine the response? Can we leverage such mechanisms to alter the course of diseases like cancer and neurodegenerative disease?
Research focus
Neural control of cell stress response pathways & transcription factors
Project 2
The roles of IL-17/ILC-17.1 and CEP-1/p53 in development, aging, and dormancy
We use the metazoan C. elegans, mouse models, and mammalian cells (primary cells and cell lines) as our experimental systems.
Faculty affiliations
Join our team!
Interested in joining the Prahlad Lab? We are looking for interns, students, postdocs and research scientists at all levels.
Connect with the Prahlad Lab
Email Dr. PrahladGitHub
Department of Cell Stress Biology
Roswell Park Comprehensive Cancer Center
Elm and Carlton Streets
Buffalo, NY 14263