Thomas Tomasi, MD, PhD
Thomas Tomasi, MD, PhD
Dr. Tomasi has been a preceptor to 60 predoctoral and postdoctoral fellows.
Dr. Thomas Tomasi received his AB from Dartmouth College, with highest distinction, and his MD, cum laude, from the University of Vermont. He served as resident and chief-resident at Columbia Presbyterian Hospital, New York, NY. He received his Ph.D. from The Rockefeller University in 1965.
His faculty positions include: Chair of Experimental Medicine, University of Vermont; Buswell Professor and Director, Division of Immunology and Rheumatic Diseases; Professor of Medicine, State University of New York at Buffalo [SUNY-UB]; William H. Donner Professor and Chair of Immunology, Mayo Medical School; Distinguished University Professor and Chair of Cell Biology and Director of the University of New Mexico Cancer Center; President & CEO, Roswell Park Cancer Center [RPCI]. He is currently a Member and Professor at RPCI and Professor of Medicine and Microbiology and Immunology at SUNY-UB. Dr. Tomasi is a member of the Association of American Physicians and has been honored by the Michael Heidelberger Lectureship, Columbia University; Distinguished Alumni Award, UVM; Citizen of the Year Awards, Buffalo, NY; George F. Koepf Award, Hauptman-Woodward Research Institute; D'Youville College Health Achievement Award; Honorary Doctorate, State University of New York. He has served on a number of scientific editorial boards including: Journal of Immunology; Journal of Clinical Investigation; Journal of Medicine; Journal of Clinical Immunology and the Advisory Board for Critical Reviews in Immunology.
He served as a member of the Board of Trustees, Trudeau Institute for Medical Research, Saranac Lake, NY; Board of Directors, Western New York Technology Development Center, Inc.; Board of Trustees, Calspan/UB Research Center; and the Scientific Advisory Board, Guthrie Research Institute.
- Development of epigenetic tumor vaccine.
- Examining the pathways by which micro RNAs regulate immune genes.
Oshlag JZ, Devasthanam AS, Tomasi TB. Mild hyperthermia enhances the expression and induces oscillations in the Dicer protein. International j hyperthermia. 2013, 29(1): 51-61
Devasthanam AS and Tomasi TB. Dicer in immune cell development and function. Immunological investigations. 2014, 48(2): 182-195
Tomasi TB, Magner WJ, Wiesen JL, Oshlag JZ, Cao F, Pontikos AN, Gregorie CJ. MHC class II regulation by epigenetic agents and microRNAs. Immunologic research 2010; 46(1-3):45-58
Asirvatham AJ, Magner WJ, Tomasi TB. miRNA regulation of cytokine genes.Cytokine 2009; 45(2):58-69
Gregorie CJ, Wiesen JL, Magner WJ, Lin AW, Tomasi TB. Restoration of immune response gene induction in trophoblast tumor cells associated with cellular senescence. Journal of reproductive immunology 2009; 81(1):25-33
Wiesen JL, Tomasi TB. Dicer is regulated by cellular stresses and interferons.Molecular immunology 2009; 46(6):1222-1228
Asirvatham AJ, Gregorie CJ, Hu Z, Magner WJ, Tomasi TB. MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components.Molecular immunology 2008; 45(7):1995-2006
Chou SD, Tomasi TB. Spatial distribution of histone methylation during MHC class II expression. Molecular immunology 2008; 45(4):971-980
Khan AN, Gregorie CJ, Tomasi TB. Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cells.Cancer immunology, immunotherapy : CII 2008; 57(5):647-654
Khan AN, Tomasi TB. Histone deacetylase regulation of immune gene expression in tumor cells. Immunologic research 2008; 40(2):164-178
Khan AN, Magner WJ, Tomasi TB. An epigenetic vaccine model active in the prevention and treatment of melanoma. Journal of translational medicine 2007;5:64