Matthew Benesch


About Matthew Benesch


I am Canadian, having completed my MD and PhD at the University of Alberta in Edmonton, Alberta, and my MPH at Harvard University concurrently with my general surgery residency at Memorial University of Newfoundland in St. John's, Newfoundland and Labrador. My research interests include the epidemiology of and associations among rare cancers, and the development and study of novel compounds that target cancer treatment resistance.


Roswell Park Comprehensive Cancer Center

  • Complex General Surgical Oncology Fellow
  • Department of Surgical Oncology


Education and Training:

  • 2018-2020 - MPH - Epidemiology, Harvard University, Boston, MA
  • 2012-2015 - PhD - Biochemistry, University of Alberta, Edmonton, Canada
  • 2010-2017 - MD - University of Alberta, Edmonton, Canada


  • 2017-2022 - General Surgery, Memorial University of Newfoundland, St. John's, Canada

Board Certification:

  • 2022 - Fellow of the Royal College of Surgeons of Canada
  • 2022 - American Board of Surgery

Professional Memberships:

  • Society of Surgical Oncology
  • Canadian Society of Surgical Oncology
  • Canadian Association of General Surgeons
  • American College of Surgeons
  • Society of American Gastrointestinal and Endoscopic Surgeons

Honors & Awards:

  • 2015 - Governor General’s Gold Medal
  • 2014 - Alberta Science and Technology (AsTech) Leaders of Tomorrow Winner
  • 2011 - Vanier Canada Graduate Scholarship


Full Publications list on PubMed

Benesch MGK, Bursey SR, O'Connell AC, Ryan MG, Howard CL, Stockley CC, Mathieson A. CDH1 Gene Mutation Hereditary Diffuse Gastric Cancer Outcomes: Analysis of a Large Cohort, Systematic Review of Endoscopic Surveillance, and Secondary Cancer Risk Postulation. Cancers. 2021 May 26;13(11). doi: 10.3390/cancers13112622. PubMed PMID: 34073553; PubMed Central PMCID: PMC8199234.

Benesch MGK, Mathieson A. Epidemiology of Mucinous Adenocarcinomas. Cancers. 2020 Oct 30;12(11). doi: 10.3390/cancers12113193. PubMed PMID: 33143115; PubMed Central PMCID: PMC7692300.

Benesch MGK, Mathieson A. Epidemiology of Signet Ring Cell Adenocarcinomas. Cancers. 2020 Jun 11;12(6). doi: 10.3390/cancers12061544. PubMed PMID: 32545410; PubMed Central PMCID: PMC7352645.

Benesch MGK, Tang X, Brindley DN. Autotaxin and Breast Cancer: Towards Overcoming Treatment Barriers and Sequelae. Cancers. 2020 Feb 6;12(2). doi: 10.3390/cancers12020374. Review. PubMed PMID: 32041123; PubMed Central PMCID: PMC7072337.

Benesch MG, Tang X, Dewald J, Dong WF, Mackey JR, Hemmings DG, McMullen TP, Brindley DN. Tumor-induced inflammation in mammary adipose tissue stimulates a vicious cycle of autotaxin expression and breast cancer progression. FASEB J. 2015 Sep;29(9):3990-4000. doi: 10.1096/fj.15-274480. Epub 2015 Jun 12. PubMed PMID: 26071407.