Inflammatory Breast Cancer

Inflammatory breast cancer is a rare breast cancer type, representing only 1% to 5% of all breast cancers. It tends to affect younger women more than older (post menopause) women, and affects black women more than white women.

Inflammatory breast cancer is characterized by a sudden onset of symptoms that make the breast look and feel inflamed — swelling, redness and the sensation that the breast is heavy and warm. Other symptoms include itchiness, an inverted or retracted nipple, and thickening or pitting of the skin, causing it to resemble an orange peel.

With inflammatory breast cancer, the cancer cells grow rapidly and block the lymph vessels to the skin, resulting in the sudden swelling, redness and other inflammatory symptoms.

Treatment for Inflammatory Breast Cancer

Because of the rapid and aggressive growth, many cases are already advanced at diagnosis. Inflammatory breast cancer is typically determined to be at least Stage IIIB. Treatment will often involve several treatment approaches, such as chemotherapy, surgery, radiation therapy, HER2 targeted therapy and immunotherapy. Consultation with a multidisciplinary team is essential to determining the appropriate treatment — and the optimal sequence of treatment — for you.

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