Dr. Prahlad’s research has been published in numerous high-profile journals, including Science, Proceedings of the National Academy of Sciences, Molecular Cell, Cell Reports, Journal of Neurogenetics, Journal of Cell Science and Elife.
piRNAs safeguard splicing and RNA fidelity during heat shock
- Journal: bioRxiv, October 2025 (preprint)
- Authors: Min S, Cruz-Corchado J, Prahlad V.
- Citation: bioRxiv [Preprint]. 2025 October 27:2025.10.27.684940. doi: 10.1101/2025.10.27.684940
Neuronal IL-17 controls Caenorhabditis elegans developmental diapause through CEP-1/p53
- Journal: Proceedings of the National Academy of Sciences USA, March 2024
- Authors: Godthi A, Min S, Das S, Cruz-Corchado J, Deonarine A, Misel-Wuchter K, Issuree PD, Prahlad V.
- Citation: Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2315248121. doi: 10.1073/pnas.2315248121.
- Das S, Min S, Prahlad V. Gene bookmarking by the heat shock transcription factor programs the insulin-like signaling pathway. Mol Cell. 2021 Dec 2;81(23):4843-4860.e8. doi: 10.1016/j.molcel.2021.09.022.
- Das S, Ooi FK, Cruz Corchado J, Fuller LC, Weiner JA, Prahlad V. Serotonin signaling by maternal neurons upon stress ensures progeny survival. Elife. 2020 Apr 23;9:e55246. doi: 10.7554/eLife.55246.
- Cruz-Corchado J, et al. Global Transcriptome Changes That Accompany Alterations in Serotonin Levels in Caenorhabditis elegans. G3 (Bethesda). 2020 Apr 9;10(4):1225-1246. doi: 10.1534/g3.120.401088.
- Ooi FK, Prahlad V. Olfactory experience primes the heat shock transcription factor HSF-1 to enhance the expression of molecular chaperones in C. elegans. Sci Signal. 2017 Oct 17;10(501):eaan4893. doi: 10.1126/scisignal.aan4893.
- Chikka MR, Anbalagan C, Dvorak K, Dombeck K, Prahlad V. The Mitochondria-Regulated Immune Pathway Activated in the C. elegans Intestine Is Neuroprotective. Cell Rep. 2016 Aug 30;16(9):2399-414. doi: 10.1016/j.celrep.2016.07.077.
- Tatum MC, et al. Neuronal serotonin release triggers the heat shock response in C. elegans in the absence of temperature increase. Curr Biol. 2015 Jan 19;25(2):163-174. doi: 10.1016/j.cub.2014.11.040.
- Prahlad V, Morimoto RI. Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins. Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14204-9. doi: 10.1073/pnas.1106557108.
- Prahlad V, Cornelius T, Morimoto RI. Regulation of the cellular heat shock response in Caenorhabditis elegans by thermosensory neurons. Science. 2008 May 9;320(5877):811-4. doi: 10.1126/science.1156093.
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Department of Cell Stress Biology
Roswell Park Comprehensive Cancer Center
Elm and Carlton Streets
Buffalo, NY 14263