Cancers Treated:
Research Interests:
- SBRT (Stereotactic Body Radiation Therapy)
- Novel agents to improve radiation therapy
- Novel agents to protect against side effects of radiation therapy
- Development and implementation of imaging to improve radiation targeting
- Methods to improve quality of life following radiation therapy
- Impact of nutrition on patient outcomes
Positions
Roswell Park Comprehensive Cancer Center
- Professor of Oncology
- Director, Radiation Research
- Director, Head & Neck and Lymphoma Radiation Services
- Associate Dean of Graduate Medical Education, Radiation Medicine
- Department of Radiation Medicine
- Co-Leader, Cancer Stress Biology Program
Jacobs School of Medicine and Biomedical Sciences, University at Buffalo
- Professor of Medicine
Background
Education and Training
- MD - Washington University School of Medicine, St. Louis, MO
- BS - Yale University
Residency
- Mallinckrodt Institute of Radiology, St. Louis, MO
Board Certification
- Radiation Oncology, American Board of Radiology
Professional Experience
- 09/2012-Present - Professor of Medicine, University at Buffalo
- 07/2012-Present - Professor of Oncology, Director of Radiation Research, Roswell Park Cancer Institute
- 07/2007–07/2012 - Associate Professor, Director of Radiation Medicine Residency Program, Director of Radiation Research, Roswell Park Cancer Institute, University at Buffalo
- 07/2004-06/2007 - Attending Physician, Head of Molecular Imaging Section, Radiation Oncology Branch, National Cancer Institute
Honors & Awards
- 2013-2023 - Buffalo Spree Top Doctors
- 2013-2020 - Top Doctors in Western New York (Castle Connolly)
- 2021 - Walter T. Murphy Educator of the Year Award
- 2020 - Educator of the Year (2019-2020), Association of Residents In Radiation Oncology (ARRO)
- 2017 - ASTRO Basic/Translational Science Abstract Award, Sr. Investigator in the Clinical category for, “A Pilot Study of Stereotactic Body Radiation Therapy Combined With Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma.”
- 2016 - Walter T. Murphy Educator of the Year Award given by the Radiation Medicine residents for excellence in clinical education
- 2016 - Commendation from ACGME Residency Progam Review: No citations & excellent compliance
- 2015 - Commendation from ACGME Residency Progam Review: No citations & excellent compliance
- 2011 Outstanding Accreditation Award from University at Buffalo, No citations and Commendable Practice ACGME Residency Program Review
- 2010 - Educator of the Year (2009-2010), Association of Residents In Radiation Oncology (ARRO)
- 2006 - CaPSure Mentor (for Nicole SImone)
- 1995 - MENSA Research and Education Scholarship
- 1995 - Magna Cum Laude Graduate, Yale University
- 1994 - MENSA Research and Education Scholarship
- 1994 - Xerox Technical Merit Scholarship
Research Overview
Dr. Singh's research seeks to improve patient survival and/or quality of life. Partnerships with basic scientists, epidemiologists, statisticians, physicians from other specialties, and hosts of additional experts develop novel, cutting edge care strategies which are then tested in clinical trials. Projects range from the ways radiation impacts the immune system immune system to new agents and approaches to limit the side effects of chemotherapy and radiation.
Clinical Trials
Featured on CancerTalk
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Publications
Representative Publications:
1. Chow J, Khan A, Gaudieri M, Wasik BJ, Conway A, Soh KT, Repasky EA, Schwaab T, Wallace PK, Abrams SI, Singh AK, Muhitch JB. Tumor and immune remodeling following radiotherapy in human renal cell carcinoma. J Immunother Cancer. 2023 Apr;11(4). doi: 10.1136/jitc-2022-006392. PubMed PMID: 37080610.
2. *Ma SJ, *Gill J, *Waldman O, *Yendamuri K, *Dunne-Jaffe C, *Chatterjee U, *Fekrmandi F, *Shekher R, *Iovoli A, Yao S, Oladeru OT, Singh AK. Association of Neighborhood-Level Household Income With 21-Gene Recurrence Score and Survival Among Patients With Estrogen Receptor-Positive Breast Cancer. JAMA Netw Open. 2023 Feb 1;6(2):e230179. doi: 10.1001/jamanetworkopen.2023.0179. PubMed PMID: 36809469; PubMed Central PMCID: PMC9945075.
3. *Ma SJ, Yu H, *Yu B, *Waldman O, *Khan M, *Chatterjee U, *Santhosh S, *Gill J, *Iovoli AJ, *Farrugia M, Shevorykin A, Carl E, Wooten K, Gupta V, McSpadden R, Kuriakose MA, Markiewicz MR, Al-Afif A, Hicks WL Jr, Platek ME, Seshadri M, Sheffer C, Warren GW, Singh AK. Association of Pack-Years of Cigarette Smoking With Survival and Tumor Progression Among Patients Treated With Chemoradiation for Head and Neck Cancer. JAMA Netw Open. 2022 Dec 1;5(12):e2245818. doi: 10.1001/jamanetworkopen.2022.45818. PubMed PMID: 36480200.
4. *Ma SJ, Wang K, *Iovoli AJ, Attwood K, Hermann GM, *Farrugia MK, Singh AK. Association of gabapentin with pain control and feeding tube placement among patients with head and neck cancer receiving chemoradiotherapy. JAMA Netw Open. 2022;5(5):e2212900. doi:10.1001/jamanetworkopen.2022.12900. PubMed PMID: 35583872.
5. Chen M, Qiao G, Hylander BL, Mohammadpour H, Wang XY, Subjeck JR, Singh AK, Repasky EA. Adrenergic stress constrains the development of anti-tumor immunity and abscopal responses following local radiation. Nat Commun. 2020 Apr 14;11(1):1821. doi: 10.1038/s41467-020-15676-0. PubMed PMID: 32286326.