Future Treatments for Uterine & Endometrial Cancer

  • Kunle Odunsi, MD, PhD, FRCOG, FACOG, Chair, Department of Gynecologic Oncology, is among those at RPCI investigating alternative treatment methods for uterine cancer.

Roswell Park researchers are investigating alternative treatment methods for uterine cancer. The use of intraperitoneal (IP) chemotherapy is one of the treatments developed by Roswell Park oncologists that is also being evaluated for the treatment of uterine cancer.

IP chemotherapy uses the same drugs as intravenous (IV) chemotherapy, but they are delivered at 10 to 100 times the concentration directly to the abdomen, bathing the peritoneal cavity in anticancer agents. To facilitate this method of chemotherapy, a port is placed in the patient’s abdomen for drug delivery. Because the toxicity of the drugs is higher, side effects may be more pronounced.

Research found that adding IP chemotherapy improved progression-free survival and overall survival for ovarian cancer patients. More research is necessary to determine if IP chemotherapy will have the same positive results in the treatment of other gynecologic cancers, including uterine cancer.