Lymphoma Treatments: More Options, Better Outcomes

More Treatment Options to Better Meet Your Needs

Roswell Park now offers the FDA-approved CAR T-cell therapies Yescarta™ and Kymriah™ for specific patients with non-Hodgkin lymphoma.

The Lymphoma Service at Roswell Park follows the Clinical Practice Guidelines in Oncology™ — the National Comprehensive Cancer Network’s internationally recognized guidelines for treating different types of cancer. They are the most comprehensive, most frequently updated clinical practice guidelines available in any area of medicine. The NCCN Guidelines are developed by panels of leading experts, including Francisco Hernandez-Ilizaliturri, MD (Hodgkin Lymphoma Panel).

Experienced, Specialty-trained Faculty

Aggressive cancers like lymphoma require expert care. Dr. Hernandez-Ilizaliturri explains.

The Lymphoma Team diagnoses and treats patients with cancers of the blood, including:

Because there are many subtypes of lymphoma, seeking care from a team that specializes in lymphoma is essential. Every member of the Roswell Park Lymphoma Team has extensive subspecialty experience in diagnosing and treating lymphoma.

Types of Treatment

Treatment guidelines are critical, because treatments can vary widely for different lymphoma subtypes. They may include:

  • Watchful waiting (not receiving treatment, but monitoring the disease closely)
  • Chemotherapy
  • Targeted therapy (treatments that attack only specific parts of a cancer cell)
  • Treatments to boost the immune system response (for example, CAR T-cell therapy or monoclonal antibody therapy)
  • Radiation treatment
  • Blood or marrow transplant (BMT)

Sometimes a combination of treatments works best. The choice of treatment depends mainly on the following:

  • The precise type and subtype of your lymphoma
  • Any known genetic or molecular characteristics of your cancer
  • Whether the disease is aggressive or slow-moving, and how far it has spread
  • Symptoms
  • Whether the disease has relapsed or not responded to previous treatments
  • Your age

Targeted Therapies

In recent years, therapies that zero in on specific molecules found only on cancer cells — drugs called targeted therapies — have transformed treatment plans for many lymphoma patients. Roswell Park investigators have conducted groundbreaking research on targeted therapies for lymphoma and continue to offer clinical research studies (clinical trials) of these and other new lymphoma treatments, giving our patients access to these options before they are available at most other centers. Clinical research studies based on the latest scientific research offer great hope for improving outcomes for lymphoma patients.