One of the biggest challenges in treating ovarian cancer is the fact that most women are not diagnosed until the cancer has already advanced and five-year survival is around 30%. By contrast, early-stage disease is highly treatable, with a survival rate of 90%.
Researchers at Roswell Park Comprehensive Cancer Center have been actively engaged in the effort to develop treatments or other control strategies that can help communities worldwide to address the impacts of the COVID-19 pandemic.
In 2019, Pamela Hershberger, PhD, came upon a stunningly significant finding in her research lab. Dr. Hershberger, Associate Professor of Oncology in Roswell Park’s Department of Pharmacology and Therapeutics, says she and her team had been “studying patients with a particular type of lung cancer — EGFR mutant lung cancer — and their response to a specific class of drugs called EGFR tyrosine kinase inhibitors. The drugs were proving very effective in killing cancer cells, but typically lost their effectiveness after about a year.