Immunotherapy

“Before you begin treatment, you should feel good knowing that you have done your due diligence, you are confident that you have received the correct diagnosis, and you are comfortable with your medical team and your treatment plan,” says Dr. Frederick.
A second opinion at Roswell Park led to an immunotherapy clinical trial that gave ovarian cancer patient Julia Falleti more time with her family.
Dr. Clinton willingly traveled from Ohio to Buffalo every month, and sometimes more often, because the clinical trial “was the most advanced immunological treatment for my genetic type of cancer.
“Other than a shot once a month, I’m in no pain,“ Judi says. “Instead, I’ve already lived three years longer than I thought I would at the beginning of this diagnosis. I’m happy to be alive and feeling well, and one day, I hope to ring that Victory Bell at Roswell Park.”
“It’s so easy, I feel like I’m getting away with something.” That’s how Nella Smolinksi describes the last three years of treatment with an immunotherapy drug to control her rare form of Hodgkin lymphoma.

2020 was shaping up to be a busy and exciting year for Pawel Kalinski, MD, PhD, Vice Chair for Translational Research at Roswell Park, and his team at the Center of Immunology.

Learn how the side effects of immunotherapy may differ from those of chemotherapy.
"It’s the potential to provide simple and effective methods to protect against disease and cancer. That’s what has always been very important to me.”
Patients with diffuse large B-cell lymphoma (DLBCL) that did not respond to treatment or that came back after two previous treatments had few remaining options — until now.

In 2006, Shinya Yamanaka, a Japanese stem cell researcher, made a groundbreaking discovery that would win him the Nobel Prize. Yamanaka discovered a new way to turn adult, dividing cells into pluripotent stem cells.

“For me, it’s kind of a miracle. I have the second chance in life that I never thought I’d have.”

Dr. Lee says hopes are high for the success of immunotherapies targeting multiple myeloma: “I think we’re seeing a major change in the way we take care of the disease.”