Smoldering Multiple Myeloma

Smoldering multiple myeloma (SMM) is a condition in which there are higher-than-normal levels of M-protein and plasma cells in your bone marrow. Even though SMM does not cause the signs and symptoms of multiple myeloma, most people with SMM will eventually develop multiple myeloma.


Patients with smoldering multiple myeloma who have no symptoms, or very mild symptoms, may be able to delay the start of cancer treatment for a while. By delaying treatment, you can avoid treatment side effects until you experience symptoms. If you and your doctor agree that this is a good idea, you will have frequent checkups so you can begin treatment promptly if your disease begins to progress. This is called active surveillance or watchful waiting.

To arrange for a second opinion, call 1-800-ROSWELL (1-800-767-9355) or fill out the online Become a Patient Form.