Exciting discoveries from the Chakraborty Lab can be found in reputed journals, including Nature Communications, Nature Materials, Cell Reports Medicine, Cell Reports, PNAS, and PloS Pathogens.

Figure from a scientific research study

YAP/TAZ Drive Agrin-Matrix Metalloproteinase-12 Mediated Diabetic Skin Wound Healing

  • Publication: Journal of Investigative Dermatology, May 2024
  • Authors: Yu Lin MO, Sampath D, Bosykh DA, Wang C, Wang X, Subramaniam T, Han W, Hong W, Chakraborty S.
  • Citation: J Invest Dermatol. 2024 May 27:S0022-202X(24)00391-9. doi: 10.1016/j.jid.2024.05.005. Epub ahead of print. PMID: 38810954.

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The extracellular matrix in hepatocellular carcinoma: Mechanisms and therapeutic vulnerability

  • Publication: Cell Reports Medicine, August 2023
  • Authors: Roy AM, Iyer R, Chakraborty S
  • Citation: Cell Rep Med. 2023 Aug 25:101170.

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The Hippo Pathway Effectors YAP/TAZ-TEAD Oncoproteins as Emerging Therapeutic Targets in the Tumor Microenvironment

  • Publication: Cancers (Basel), July 2023
  • Authors: Mokhtari RB, Ashayeri N, Baghaie L, Sambi M, Satari K, Baluch N, Bosykh DA, Szewczuk MR, Chakraborty S
  • Citation: Cancers (Basel). 2023 Jul 2;15(13):3468.

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Agrin-Matrix Metalloproteinase-12 axis confers a mechanically competent microenvironment in skin wound healing

  • Publication: Nature Communications, November 2021
  • Authors: Chakraborty S, Sampath D, Ong Yu-Lin M, Bilton M, Huang CK, Njah K, Goy P, Wang C, Guccione E, Lim CT and Wanjin Hong
  • Citation: Nat Commun. 2021 Nov 3;12(1):6349.

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Agrin Mediates Angiogenesis in the Tumor Microenvironment

  • Publication: Trends in Cancer, February 2020
  • Authors: Chakraborty S, Njah K, Hong W
  • Citation: Trends Cancer. 2020 Feb;6(2):81-85.

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A role of Agrin in maintaining the stability of vascular endothelial receptor-2 during tumor angiogenesis

  • Publication: Cell Reports, July 2019
  • Authors: Chakraborty S, Njah K, Qiu B, Arumugam S, Lakshmanan M, Tergaonkar V, Thibault G, Wang X, Hong W
  • Citation: Cell Rep. 2019 Jul 23;28(4):949-965.e7.

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Agrin as a mechanotransduction signal regulating YAP through the Hippo pathway

  • Publication: Cell Reports, March 2017
  • Authors: Chakraborty S, Kizito N, Pobbati AV, Lim YB, Raju A, Lakshmanan M, Tergaonkar V, Lim CT, Hong W
  • Citation: Cell Rep. 2017 Mar 7;18(10):2464-2479.

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An oncogenic role of Agrin in regulating focal adhesion integrity in hepatocellular carcinoma

  • Publication: Nature Communications, January 2015
  • Authors: Chakraborty S, Lakshmanan M, Swa HL, Chen J, Zhang X, Ong YS, Loo LS, Gunaratne J, Tergaonkar V, Hui KM, Hong W
  • Citation: Nat Commun. 2015 Jan 29;6:6184.

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Department of Pharmacology & Therapeutics
Roswell Park Comprehensive Cancer Center
Elm and Carlton Streets
Buffalo, NY 14263