Figure from a scientific research study

Pharmacologically targeting KRAS G12D in PDAC models: tumor cell intrinsic and extrinsic impact

  • Journal: bioRxiv [preprint], April 2023
  • Authors: Kumarasamy V, Frangou C, Wang J, Wan Y, Dynka A, Rosenheck H, Dey P, Abel EV, Knudsen ES, Witkiewicz AK.
  • Citation: 2023 Apr 20:2023.03.18.533261. doi: 10.1101/2023.03.18.533261.
PubMedFull text
Figure from a scientific research study

ATDC binds to KEAP1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer

  • Journal: Genes & Development, February 2021
  • Authors: Purohit V, Wang L, Yang H, Li J, Ney GM, Gumkowski ER, Vaidya AJ, Wang A, Bhardwaj A, Zhao E, Dolgalev I, Zamperone A, Abel EV, Magliano MPD, Crawford HC, Diolaiti D, Papagiannakopoulos TY, Lyssiotis CA, Simeone DM.
  • Citation: Genes Dev. 2021 Feb 1;35(3-4):218-233. doi: 10.1101/gad.344184.120.
PubMedFull text
Figure from a scientific research study

Beta 1 integrin signaling mediates pancreatic ductal adenocarcinoma resistance to MEK inhibition

  • Journal: Scientific Reports, July 2020
  • Authors: Brannon A 3rd, Drouillard D, Steele N, Schoettle S, Abel EV, Crawford HC, Pasca di Magliano M.
  • Citation: Sci Rep. 2020 Jul 7;10(1):11133. doi: 10.1038/s41598-020-67814-9.
PubMedFull text
Figure from a scientific research study

HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties

  • Journal: eLife, August 2018
  • Authors: Abel EV, Goto M, Magnuson B, Abraham S, Ramanathan N, Hotaling E, Alaniz AA, Kumar-Sinha C, Dziubinski ML, Urs S, Wang L, Shi J, Waghray M, Ljungman M, Crawford HC, Simeone DM. 
  • Citation: Elife. 2018 Aug 3;7:e33947. doi: 10.7554/eLife.33947.
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Department of Molecular & Cellular Biology
Roswell Park Comprehensive Cancer Center  
Elm and Carlton Streets  
Buffalo, NY 14263  

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