Philip McCarthy, MD

Professor of Oncology and Internal Medicine
Director, Transplant & Cellular Therapy Center, Department of Medicine
Roswell Park Comprehensive Cancer Center
Professor of Oncology and Internal Medicine
Jacobs School of Medicine and Biomedical Sciences, University at Buffalo
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Areas of Expertise: 
Blood Marrow Transplant
Hematologic Oncology
Acute and chronic leukemias
Aplastic Anemia
Hodgkin lymphoma (HL)
Multiple myeloma
Myelodysplastic syndromes
Non-Hodgkin lymphoma (NHL)
Testicular cancer
Special Interests: 
Health effects of radiation exposure
Modulation of chemotherapy toxicity
Modulation of graft versus host disease
Blood and marrow stem cell isolation
Immune modulation after transplantation
Cancer immunotherapy
Preclinical models of bone marrow transplantation
Models for patient outcomes after blood and marrow transplantation


My research interests are devoted to developing novel intensive and reduced intensity allogeneic and autologous hematopoietic stem cell transplant (HSCT) approaches for the treatment of hematologic disorders, leading to improved patient outcomes and decreased toxicity. I have over 20 years of experience treating HSCT patients and directing clinical and translational HSCT research studies. I have served as chair, or co-chair, of several clinical trials, including CALGB 100104, a phase III clinical trial evaluating lenalidomide maintenance after autologous HSCT for multiple myeloma (MM). This study demonstrated an improved progression-free and overall survival for MM patients receiving lenalidomide maintenance therapy after autologous HSCT. Our team has developed a systematic approach to the evaluation and treatment of HSCT patients with a specific focus on predicting and minimizing treatment-related mortality (TRM). We participate with a core group of basic science and clinical researchers who are committed to the investigation of the complications of autologous and allogeneic HSCT and to the developing novel approaches to improve outcomes.


Education and Training: 
MD - Tufts University School of Medicine, Boston, MA
Yale-New Haven Hospital, Yale University, New Haven, CT
Brigham and Women’s Hospital, Harvard University, Boston, MA
Board Certification: 
Internal Medicine, American Board of Internal Medicine
Hematology, American Board of Internal Medicine
Medical Oncology, American Board of Internal Medicine
Professional Memberships: 
American Society of Hematology (ASH)
American Society for Blood and Marrow Transplantation (ASBMT)
International Society for Cellular Therapy (ISCT)
American Society of Clinical Oncology (ASCO)
American Association of Blood Banking
American Association for Cancer Research (AACR)
Honors and Awards: 
2015-2016 Castle Connolly America’s Top Doctors, Hematology
2005-2013 Best Doctors in America

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