Jens Hillengass, MD

Professor of Oncology and Internal Medicine
Chief of Myeloma
Roswell Park Comprehensive Cancer Center
Professor of Medicine
Division of Hematology and Oncology
Jacobs School of Medicine and Biomedical Sciences, University at Buffalo
Areas of Expertise: 
Diagnostics and treatment of monoclonal plasma cell disorders
Autologous stem cell transplantation
Hemato-oncological imaging
Special Interests: 
Imaging of bone and bone marrow involvement in monoclonal plasma cell diseases
Optimizing and individualizing myeloma treatment
Early detection and characterization of monoclonal plasma cell disorders
High risk multiple myeloma and plasma cell leukemia
Physical exercise in hematological patients


While in Medical School I focused my research on the investigation of morphological and functional imaging of hematological diseases, especially monoclonal plasma cell disorders. Our group has established magnetic resonance imaging (MRI) and computed tomography (CT) as novel standard diagnostic techniques in multiple myeloma and its precursor diseases. The discovery of a heterogeneity in growth patterns in myeloma has led us to focus on the significance of a spatial heterogeneity for genomic assessment and treatment monitoring especially minimal residual disease assessment.

The huge amount of information coming from whole body imaging motivated us to start the development of software tools to support the radiologist and nuclear medicine specialist in evaluating the clinical data and to make this "big imaging data" available for research. Dealing with myeloma patients in advanced stages of the disease and analyzing imaging results of modern imaging techniques has led to a deeper interest in myeloma bone disease, where we have started to investigate the influence of physical activity on pain, quality of life and skeletal related events. Having been responsible for the largest autologous stem cell transplant program in Germany has also motivated me to investigate how treatment with high dose chemotherapy can be improved regarding outcome and tolerability.


Education and Training: 
MD - University of Heidelberg
University of Heidelberg, Internal Medicine, Hematology and Oncology
University of Heidelberg, Hematology and Oncology
German Cancer Research Center, Radiology
National Cancer Institute, short term visiting researcher
Board Certification: 
Internal Medicine
Hematology and Oncology
Professional Memberships: 
American Society of Hematology
International Myeloma Working Group
Black Swan Research Initiative
Honors and Awards: 
Gerok-Scholarship Deutsches Krebsforschungszentrum 2008
Young Masters Award der DGHO 2009
Familie Kasprzak Forschungspreis 2017
Professional Experience: 
Head of the autologous transplant program at the University of Heidelberg
Deputy head of the section multiple myeloma of the University of Heidelberg