David Mattson Jr.

Radiation Oncology
Buffalo Spree Top Doctor 2024

Dr. Mattson Jr. is a Buffalo Spree Top Doctor! See all of our physicians who made this year's list.

Top Doctors 2024

Cancers Treated:

Specializing In:

Gastrointestinal and gynecological radiotherapy Breast cancer brachytherapy and clinical research

Research Interests:

Partial breast irradiation and hypofractionated partial breast irradiation

About David Mattson Jr.


Roswell Park Comprehensive Cancer Center
  • Associate Professor of Oncology
  • Department of Radiation Medicine
  • Director, GI & GYN Radiation Services
  • Department of Indigenous Cancer Health, Native Hawaiian

Jacobs School of Medicine and Biomedical Sciences, University at Buffalo

  • Clinical Associate Professor
  • Department of Radiation Oncology


Education and Training:

  • MD - John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI


  • University Hospital, State University of New York Health Sciences Center, Syracuse, NY
  • University of Iowa Hospital & Clinics, Iowa City, IA


  • University of Iowa Hospital & Clinics, Iowa City, IA
  • National Cancer Institute, Bethesda, MD

Featured on Cancer Talk


  • Scarbrough PM, Mapuskar KA, Mattson DM, Gius D, Watson WH, Spitz DR. Simultaneous inhibition of glutathione- and thioredoxin-dependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress. Free radical biology and medicine 2012; 522:436-443
  • Wilson JP , Mattson D , Edge SB. Is there a need for axillary dissection in breast cancer? . Journal of the National Comprehensive Cancer Network : JNCCN 2011; 92:225-230
  • Mattson DM, Dornfeld KJ, Spitz DR, Orcutt KP, Li L, Aykin-Burns N, Parsons AD, Dayal D, Ahmad IM, Simons AL. Cisplatin combined with zidovudine enhances cytotoxicity and oxidative stress in human head and neck cancer cells via a thiol-dependent mechanism. Free radical biology and medicine 2009;462:232-237