Cancer Talk

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Roswell Park Researchers Identify Protein That Contributes to Racial Disparities in Prostate Cancer

Cancer researchers have long known that prostate cancer tends to be more common, more aggressive and more resistant to existing treatments in African-Americans than in Caucasian-Americans, but they’re only beginning to understand why. A Roswell Park Comprehensive Cancer Center study published today points to cellular factors that appear to be driving these disparities — mitochondrial differences that prevent formation of the cancer-killing “death wheel” apoptosome protein complex — and proposes a strategy for overcoming these factors with new therapeutic targets.
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Cupid Takes on Cancer

There wasn’t chocolate, champagne, or rose petals, there was just his hand holding mine and never letting go. His presence and unwavering support meant more to me than a silly, store-bought gift.

Patient Stories
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Roswell Park Reports New Path to Overcoming Drug Resistance in HER2-Positive Breast Cancer

The HER2 protein, which encourages the growth of cancer cells, is present in about 20% of all breast cancers. While HER2-positive breast cancers tend to be very aggressive, today the prognosis is generally very good, thanks to the introduction of HER2 inhibitors such as trastuzumab (brand name Herceptin). However, not all HER2-positive breast cancers respond to existing HER2 inhibitors.
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Roswell Park, NFMMC Launch Cancer Care Collaboration

Roswell Park Comprehensive Cancer Center and Niagara Falls Memorial Medical Center today announced a collaborative effort to greatly improve the availability of cancer care in Niagara County. The first step of the new collaborative partnership is a comprehensive thoracic clinical program.
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Genetic and Metabolic Differences May Help Explain Inconsistencies in Studies on Diet and Cancer

While research suggests that increasing dietary intake of lignans — nutrients found in whole grains, vegetables, fruits and seeds — may reduce risk of breast cancer, the findings from studies testing this hypothesis have been inconsistent. A new study from Roswell Park Comprehensive Cancer Center, published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association of Cancer Research (AACR), examines how women of different backgrounds metabolize lignans. What these scientists learned may help explain why associations between diet and breast cancer risk have been difficult to demonstrate consistently.