Based on their findings, Drs. Yendamuri and Barbi designed a phase 2 clinical trial to see whether metformin might also help prevent lung cancer in overweight or obese people who are at high risk for the disease.
Innovation Engine
Everyone inherits one copy of BRCA1 and one copy of BRCA2 from each parent. An inherited mutation in just one of those copies raises the risk for developing several types of cancer.
Isothiocyanates, found in cruciferous vegetables like broccoli, can prevent cancer cells from dividing and cause them to self-destruct through a process called apoptosis.
Every year, more than 4,000 children and teens in the U.S. develop brain and spinal cord tumors, which are second only to leukemia as the most common childhood cancers. Can SurVaxM, a pioneering brain cancer immunotherapy developed at Roswell Park, work for younger patients?
What if a patient’s own immune system could cure cancer? The idea has captivated researchers for more than a century, but only recently have we begun to realize the power of “living drugs.”
"This could provide a fantastic opportunity for improving any given cancer treatment by making it more reliable, with drugs we already have in place and simply need to repurpose from one disease to another."
A one-of-a-kind software tool, developed by Roswell Park, speeds the research process by sorting through data at astonishing speeds, even organizing information based on key patient characteristics, habits or demographics.
The Indigenous & Rural Patient Navigation program recognizes that Native people often run into roadblocks when seeking cancer screening and care.
“Immune checkpoint inhibitors can make some very lethal cancers more manageable, so patients survive longer and enjoy better quality of life.”
Cancer treatment may accelerate aging, increasing the risk of other health problems. The good news: unlike normal aging, this type may be reversible.