Robert Fenstermaker, MD
Robert Fenstermaker, MD
Professor of Neurosurgery and Oncology
Chair, Department of Neurosurgery
Director, Neuro-Oncology Program
Roswell Park Cancer Institute
Department of Neurosurgery
Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo
Areas of Expertise:
Brain Tumor Surgery
Skull Base Surgery
Pituitary Tumor Surgery
Trigeminal Neuralgia
Gamma Knife Radiosurgery
Special Interests:
Immunotherapy for the treatment of malignant brain tumors
Background
Education and Training:
MD - Northeast Ohio Medical University, Rootstown, OH
Residency:
University Hospitals of Cleveland and Case Western Reserve University School of Medicine, Cleveland, OH
Fellowship:
Case Western Reserve University School of Medicine (Biochemistry and Pharmacology) Cleveland, OH
Board Certification:
Neurological Surgery, American Board of Neurological Surgery
- Shen L, Ciesielski M, Ramakrishnan S, Miles KM, Ellis L, Sotomayor P, Shrikant P, Fenstermaker R, Pili R.Class I histone deacetylase inhibitor entinostat suppresses regulatory T cells and enhances immunotherapies in renal and prostate cancer models. PloS one 2012; 71:e30815
- Jarrett SG, Novak M, Dabernat S, Daniel JY, Mellon I, Zhang Q, Harris N, Ciesielski MJ, Fenstermaker RA, Kovacic D, Slominski A, Kaetzel DM. Metastasis suppressor NM23-H1 promotes repair of UV-induced DNA damage and suppresses UV-induced melanomagenesis. Cancer research 2012; 721:133-143
- Brem SS, Michael M, Moots PL, Morrison T, Mrugala M, Nabors LB, Newton HB, Portnow J, Raizer JJ, Recht L, Shrieve DC, Sills AK Jr, Vrionis FD, Maor MH, Loeffler JS, Bierman PJ, Brem H, Butowski N, Chamberlain MC, Chiocca EA, Deangelis LM, Fenstermaker RA, Friedman A, Gilbert MR, Hesser D, Junck L, Linette GP, Wen PY. Central nervous system cancers. Journal of the National Comprehensive Cancer Network : JNCCN 2011; 94:352-400
- Gruber TJ, Fabiano AJ, Deeb G, Lele SB, Fenstermaker RA. Intracranial meningiomas in patients with uterine sarcoma treated with long-term megestrol acetate therapy. World neurosurgery 2011;765:477.e16-477.e20
- Ciesielski MJ, Ahluwalia MS, Munich SA, Orton M, Barone T, Chanan-Khan A, Fenstermaker RA.Antitumor cytotoxic T-cell response induced by a survivin peptide mimic. Cancer immunology, immunotherapy : CII 2010; 598:1211-1221
- Yang W, Riley KJ, Wikstrand CJ, Ross BD, Fenstermaker RA, Ciesielski M, Tjarks W, Huo T, Wu G, Barth RF, Binns PJ. Convection enhanced delivery of boronated EGF as a molecular targeting agent for neutron capture therapy of brain tumors. Journal of neuro-oncology 2009; 953:355-365
- Fabiano AJ, Rigual NR, Belber CS, Fenstermaker RA. Endoscopic sellar floor reconstruction with concha bullosa bone autograft and nasal septal flap: technical case report. Minimally invasive neurosurgery : MIN 2009; 522:86-88
- Paul AK, Ciesielski MJ, Sajjad M, Wang X, Ferrone S, Abdel-Nabi H, Fenstermaker RA. Expression of HMP/AN2, a melanoma associated antigen, in murine cerebral gliomas: potential for radioimmunotargeting. Journal of neuro-oncology 2009; 941:21-30
- Wierzbicki A, Gil M, Ciesielski M, Fenstermaker RA, Kaneko Y, Rokita H, Lau JT, Kozbor D. Immunization with a mimotope of GD2 ganglioside induces CD8+ T cells that recognize cell adhesion molecules on tumor cells. Journal of immunology (Baltimore, Md. : 1950) 2008; 1819:6644-6653
- Yang W, Fenstermaker RA, Ciesielski MJ, Riley KJ, Binns PJ, Sferra TJ, Moeschberger M, Tordoff K, Tjarks W, Bandyopadhyaya AK, Swindall MR, Barth RF, Wu G, Wikstrand CJ. Molecular targeting and treatment of composite EGFR and EGFRvIII-positive gliomas using boronated monoclonal antibodies. Clinical cancer research 2008; 143:883-891
- Karampelas I, Podgorsak MB, Plunkett RJ, Fenstermaker RA. Subthalamic nucleus metastasis causing hemichorea-hemiballism treated by gamma knife stereotactic radiosurgery. Acta neurochirurgica2008; 1504:395-396; discussion 397
- Ciesielski MJ, Kozbor D, Castanaro CA, Barone TA, Fenstermaker RA. Therapeutic effect of a T helper cell supported CTL response induced by a survivin peptide vaccine against murine cerebral glioma. Cancer immunology, immunotherapy : CII 2008; 5712:1827-1835
- Karampelas I, Cole PM, Kuensting JM, Fenstermaker RA. Diagnosis and conservative management of an arteriovenous fistula of the scalp following awake craniotomy for tumor resection. Acta neurochirurgica 2007; 1497:727-728; discussion 728
- Fenstermaker RA, Ciesielski MJ. EGFR Intron Recombination in Human Gliomas: Inappropriate Diversion of V(D)J Recombination? . Current genomics 2007; 83:163-170
- Kowalczyk A, Ciesielski M, Brecher M, Fenstermaker R, Repasky E, Rokita H, Kaneko Y, Bambach B, Gil M, Wierzbicki A, Kozbor D. Induction of protective immune responses against NXS2 neuroblastoma challenge in mice by immunotherapy with GD2 mimotope vaccine and IL-15 and IL-21 gene delivery.Cancer immunology, immunotherapy : CII 2007; 569:1443-1458
- Karampelas I, Alberico RA, Plunkett RJ, Fenstermaker RA. Intratumoral hemorrhage after remote subtotal microsurgical resection and gamma knife radiosurgery for vestibular schwannoma. Acta neurochirurgica 2007; 1493:313-316; discussion 316-7
- Wu G, Ciesielski MJ, Riley KJ, Binns PJ, Sferra TJ, Christoforidis GA, Yang M, Ferketich AK, Blue TE, Khorsandi B, Tjarks W, Bandyopadhyaya AK, Swindall M, Kawabata S, Barth RF, Yang W, Fenstermaker RA. Molecular targeting and treatment of an epidermal growth factor receptor-positive glioma using boronated cetuximab. Clinical cancer research 2007; 134:1260-1268
- Chen Y, Oseroff A, Fenstermaker R, Kadish KM, Fukuzumi S, Erin T, Baumann H, Ciesielski M, Pandey SK, Liu W, Wenbo E, Zhang M, Ohkubo K, Pandey RK. Photophysical, electrochemical characteristics and cross-linking of STAT-3 protein by an efficient bifunctional agent for fluorescence image-guided photodynamic therapy. Photochemical and photobiological sciences 2007; 612:1257-1267