Regulation of Cyclin D1 Degradation by Ubiquitin-Specific Protease 27X Is Critical for Cancer Cell Proliferation and Tumor Growth
- Journal: Molecular Cancer Research
- Authors: Alam S, Zunic A, Venkat S, Feigin ME, Atanassov BS
- Citation: Mol Cancer Res. 2022 Dec 2;20(12):1751-1762. doi: 10.1158/1541-7786.MCR-22-0259. PMID: 36001804; PMCID: PMC9722596
- Kuang X, McAndrew MJ, Mustachio LM, Chen YC, Atanassov BS, Lin K, Lu Y, Shen J, Salinger A, Macatee T, Dent SYR, Koutelou E. Usp22 Overexpression Leads to Aberrant Signal Transduction of Cancer-Related Pathways but Is Not Sufficient to Drive Tumor Formation in Mice. Cancers (Basel). 2021 Aug 25;13(17):4276. doi: 10.3390/cancers13174276. PMID: 34503086; PMCID: PMC8428332.
- Aquila L, Atanassov BS. Regulation of Histone Ubiquitination in Response to DNA Double Strand Breaks. Cells. 2020 Jul 16;9(7):1699. doi: 10.3390/cells9071699. PMID: 32708614; PMCID: PMC7407225.
- Koutelou E, Wang L, Schibler AC, Chao HP, Kuang X, Lin K, Lu Y, Shen J, Jeter CR, Salinger A, Wilson M, Chen YC, Atanassov BS, Tang DG, Dent SYR. USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta. Development. 2019 Feb 22;146(4):dev174037. doi: 10.1242/dev.174037. PMID: 30718289; PMCID: PMC6398448.
- Lambies G, Miceli M, Martínez-Guillamon C, Olivera-Salguero R, Peña R, Frías CP, Calderón I, Atanassov BS, Dent SYR, Arribas J, García de Herreros A, Díaz VM. TGFβ-Activated USP27X Deubiquitinase Regulates Cell Migration and Chemoresistance via Stabilization of Snail1. Cancer Res. 2019 Jan 1;79(1):33-46. doi: 10.1158/0008-5472.CAN-18-0753. Epub 2018 Oct 19. PMID: 30341066; PMCID: PMC9386731.
- Lan X, Atanassov BS, Li W, Zhang Y, Florens L, Mohan RD, Galardy PJ, Washburn MP, Workman JL, Dent SYR. USP44 Is an Integral Component of N-CoR that Contributes to Gene Repression by Deubiquitinating Histone H2B. Cell Rep. 2016 Nov 22;17(9):2382-2393. doi: 10.1016/j.celrep.2016.10.076. PMID: 27880911; PMCID: PMC5131803.
- Li W, Atanassov BS, Lan X, Mohan RD, Swanson SK, Farria AT, Florens L, Washburn MP, Workman JL, Dent SYR. Cytoplasmic ATXN7L3B Interferes with Nuclear Functions of the SAGA Deubiquitinase Module. Mol Cell Biol. 2016 Oct 28;36(22):2855-2866. doi: 10.1128/MCB.00193-16. PMID: 27601583; PMCID: PMC5086525.
- Atanassov BS, Mohan RD, Lan X, Kuang X, Lu Y, Lin K, McIvor E, Li W, Zhang Y, Florens L, Byrum SD, Mackintosh SG, Calhoun-Davis T, Koutelou E, Wang L, Tang DG, Tackett AJ, Washburn MP, Workman JL, Dent SY. ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth. Mol Cell. 2016 May 19;62(4):558-71. doi: 10.1016/j.molcel.2016.03.030. Epub 2016 Apr 28. PMID: 27132940; PMCID: PMC4874879.
Connect with the Atanassov Lab
Email: Boyko.Atanassov@RoswellPark.org
Office Phone: 716-845-3037
Lab Location: Center for Genetics & Pharmacology (CGP) L4-321
Department of Pharmacology & Therapeutics
Roswell Park Comprehensive Cancer Center
Elm and Carlton Streets
Buffalo, NY 14263