A team of researchers at Roswell Park Comprehensive Cancer Center, led by Dhyan Chandra, PhD, have uncovered evidence that could lead to the development of a new treatment option for patients with metastatic, resistant or recurrent prostate cancer. Their findings, published today in the Journal of Clinical Investigation, suggest that mitochondrial unfolded protein response — a unique longevity function of mitochondria — could be a new target for the treatment and management of this patient population.