Search
News
Metabolic Pathway Can Be Effectively Targeted to Treat Prostate Cancer, Roswell Park Team Shows
… pathway and the methionine salvage pathway. Dominic Smiraglia, PhD , Associate Professor of Oncology in the … and clinicians with no more good options,” says Dr. Smiraglia. “This new metabolic approach is completely … any tissue, and this increases with prostate cancer,” Dr. Smiraglia notes. “This unique but normal state means …
Research
Research Focus
… cured. Members: Scott Abrams, Andrei Bakin, Anna Bianchi-Smiraglia, Gokul Das, Subhamoy Dasgupta, Sharon Evans, Jia … for individualized intervention. Members: Anna Bianchi-Smiraglia, Gokul Das, Subhamoy Dasgupta, Xuhang Liu … of leverage for anti-breast cancer therapy. Anna Bianchi-Smiraglia, PhD Tumor evolution Understanding the mechanisms …
News
Roswell Park Research Identifies a Key Pathway Fueling Cancer Metastasis
… process pivotal for cancer cell invasion. Dr. Anna Bianchi-Smiraglia “The ability of cancer cells to invade is a prerequisite for metastasis,” says Anna Bianchi-Smiraglia, PhD , Assistant Professor of Oncology in the … locations to fuel cancer and metastasis,” says Dr. Bianchi-Smiraglia. “Disabling such interactions may provide a new …
News
Roswell Park Team Develops New Method of Tracking Cellular Changes Associated with Cancer
… and personalized therapies. A research team led by Dominic Smiraglia, PhD , Associate Professor of Oncology in the … potential responders to metabolic therapeutics,” says Dr. Smiraglia, who is senior author of the study. “Our data … first author of the study and a doctoral student in Dr. Smiraglia’s lab. “The magnitude of distortion of a particular …
Blog Post
Donor funding paves the way for innovative research
… stress in prostate cancer to impact the epigenome Dominic Smiraglia, PhD Led by Dominic Smiraglia, PhD Patients with advanced stage prostate cancer … their tumor adapts to treatment and becomes resistant. Dr. Smiraglia will leverage metabolic stress to target that …
Cancer Genomics and Computational Oncology PhD Track
… Mentor First Author Publication Hayley Affronti 2018 Dr. Smiraglia PubMed Charles Manhardt 2018 Dr. Lau PubMed Laura … Mussell 2020 Dr. Shang PubMed Spencer Rosario 2020 Dr. Smiraglia PubMed Renyuan Zhang 2022 Dr. Nastiuk PubMed Justine Jacobi 2023 Dr. Smiraglia PubMed Additional information about our research …
Cancer Stress Biology Research Program Members
… Co-Leader, Cancer Stress Biology Program Anna Bianchi-Smiraglia, PhD Assistant Professor of Oncology Department of … Member Department of Cancer Genetics and Genomics Dominic Smiraglia, PhD Associate Professor of Oncology Director of … Member Department of Cell Stress Biology View the Smiraglia Lab Joseph Spernyak, PhD Co-director, Translational …
Cell Stress and Biophysical Oncology Graduate Program Faculty & Staff
… PhD, DSci Department of Cell Stress Biology Anna Bianchi-Smiraglia, PhD Department of Cell Stress Biology Sayan …
Cancer Genomics and Computational Oncology PhD Track Faculty and Staff
… Oncology PhD Track Faculty and Staff Leadership Dominic Smiraglia, PhD Department of Cell Stress Biology Irwin …
News
Roswell Park Researchers Receive More Than $3.3 Million in Grant Support for Cancer Research Efforts
… the Department of Molecular and Cellular Biology, Dominic Smiraglia, PhD , Associate Professor of Oncology in the … genesis and spread of pancreatic islet-cell cancer. Dr. Smiraglia also received a two-year, $165,000 grant from the … the Department of Molecular and Cellular Biology, Dominic Smiraglia, PhD , Associate Professor of Oncology in the …