James Thompson, MD, MS James Thompson, MD, MS

James Thompson

Hematologic Oncology

Specializing In:

Acute lymphoblastic leukemia (ALL) Acute myeloid leukemia (AML) Chronic myeloid leukemia (CML) Hematologic Oncology Myelodysplastic syndrome (MDS) Myeloproliferative diseases (MPD)

Special Interests:

Etiology of MDS and unexplained anemia (UA) of aging Role of mitochondrial DNA (mtDNA) mutations in immunosenescence Role of mtDNA mutations in the development of MDS and UA

About James Thompson


Roswell Park Comprehensive Cancer Center
  • Assistant Professor, Department of Medicine


Education and Training:

  • MD - Columbia University College of Physicians & Surgeons, New York, NY
  • MS - Medical Informatics, Northwestern University, Evanston, IL


  • University of Pennsylvania, Philadelphia, PA


  • University of Pennsylvania, Philadelphia, PA

Board Certification:

  • Hematology, American Board of Internal Medicine
  • Medical Oncology, American Board of Internal Medicine
  • Internal Medicine, American Board of Internal Medicine

Clinical Trials


Full Publications list on PubMed
  • Erdogan B, Carroll M, Thompson JE, Baldwin DA, Tobias J, Isett RB, Rinker E, Tedesco J, Qualtieri J, Facey C, Kim AS. Diagnostic microRNAs in myelodysplastic syndrome. Experimental hematology 2011;399:915-926.e2
  • Safdar A, Prolla TA, Kujoth GC, Mocellin NJ, Melov S, Thompson JE, Akhtar M, Hettinga BP, Little JP, Ogborn DI, Bourgeois JM, Tarnopolsky MA. Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice. Proceedings of the National Academy of Sciences of the United States of America 2011; 10810:4135-4140
  • Greenberg PL, Maness LJ, Millenson M, Nimer SD, O'Donnell MR, Schroeder MA, Shami PJ, Stone RM,Thompson JE, Komrokji R, Head D, Gore SD, Attar E, Bennett JM, Bloomfield CD, De Castro CM, Deeg HJ, Foran JM, Gaensler K, Garcia-Manero G, Westervelt P. Myelodysplastic syndromes. Journal of the National Comprehensive Cancer Network : JNCCN 2011; 91:30-56
  • Noor SJ, Wang ES, Thompson JE, Block AW, Sait SN, Barcos M, Ford LA, Wilding GE, Tan W, Wetzler M.Myeloid blastic transformation of myeloproliferative neoplasms--a review of 112 cases. Leukemia research 2011; 355:608-613
  • Lee HJ, Thompson JE, Wang ES, Wetzler M. Philadelphia chromosome-positive acute lymphoblastic leukemia: current treatment and future perspectives. Cancer 2011; 1178:1583-1594
  • Kinder M, Thompson JE, Wei C, Shelat SG, Blair IA, Carroll M, Pure E. Interferon regulatory factor-8-driven myeloid differentiation is regulated by 12/15-lipoxygenase-mediated redox signaling.Experimental hematology 2010; 3811:1036-1046.e1-4
  • Chen ML, Carroll M, Kundu M, Selak MA, Prolla TA, Kujoth GC, Tan W, Wilding GE, Yu X, Shelat SG, Hochberg ML, Logan TD, Thompson JE. Erythroid dysplasia, megaloblastic anemia, and impaired lymphopoiesis arising from mitochondrial dysfunction. Blood 2009; 11419:4045-4053

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