Dominic Smiraglia, PhD

Associate Professor of Oncology
Department of Cancer Genetics and Genomics
Director of Graduate Studies, Cellular and Molecular Biology PhD program
Roswell Park Comprehensive Cancer Center
Special Interests: 
DNA methylation and epigenetics in cancer and normal cells
Epigenetic regulation of androgen receptor signaling
Role of folate metabolism in prostate cancer genomic and epigenomic stability


Dominic J. Smiraglia, PhD, joined the Roswell Park Comprehensive Cancer Center faculty in 2003 as an Assistant Member in the Department of Cancer Genetics.

Dr. Smiraglia comes to Roswell Park from the Division of Human Cancer Genetics at the Ohio State University (OSU), where he served as a Postdoctoral Fellow and as a Research Scientist. He earned his doctoral degree in the Department of Cell and Molecular Biology in 1997 from Roswell Park's Graduate Division and completed postdoctoral training in the Department of Molecular Virology, Immunology and Medical Genetics at OSU.

Dr. Smiraglia is a member of The DNA Methylation Society, The American Association for Cancer Research, and the Society for Basic Urological Research. He has authored or co-authored more than 50 journal publications and book chapters. He is an ad hoc reviewer for numerous journals including the Journal of Medical Genetics, Cancer Research, Blood, Oncogene and Oncology.


Education and Training: 
BA - State University of New York at Buffalo
PhD - Roswell Park Comprehensive Cancer Center, Buffalo, NY
The Ohio State University, Department of Molecular Virology, Immunology, and Medical Genetics, Division of Human Cancer Genetics