Wiam Bshara, MD

Specialty: Pathology
Biorepository and Laboratory Services (BLS) Shared Resource

Specializing In:

  • Breast cancer
  • Prostate cancer
  • Gynecologic cancers

Research Interests:

  • Basic and translational research in gynecologic, breast and genitourinary cancers
  • Image analysis

Biography

I am a research pathologist in the Department of Pathology and Laboratory Medicine. I am focused on supporting the research effort at Roswell Park providing his pathology expertise to assist investigators with their research projects and grants. I work very closely with the faculty and staff in at the Biorepository and Laboratory Services (BLS) shared resource and leads the quality control and tissue selection process to fulfil researchers tissue need. In addition, I provide support and pathological expertise to the tissue procurement team, the histology lab staff, the Tissue Microarray (TMA) laboratory as well as the Image Scanning and Analysis Laboratory.

 

Positions

Roswell Park Comprehensive Cancer Center

  • Research Pathologist
  • Department of Pathology & Laboratory Medicine
  • Biorepository and Laboratory Services (BLS) Shared Resource

Background

Education and Training

  • 1989-1995 - Tishreen University School of Medicine, Lattakia, Syria

Residency

  • 2002-2005 - State University of New York at Buffalo, Buffalo, NY
  • 2000-2002 - Allegheny General Hospital, Pittsburgh, PA
  • 1996-1998 - Damascus University, Damascus, Syria

Fellowship

  • 2005-2007 - Roswell Park Cancer Institute, Buffalo, NY

Publications

  Full Publications list on PubMed

Hait NC, Maiti A, Wu R, Andersen VL, Hsu CC, Wu Y, Chapla DG, Takabe K, Rusiniak ME, Bshara W, Zhang J, Moremen KW, Lau JTY. Extracellular sialyltransferase st6gal1 in breast tumor cell growth and invasiveness. Cancer Gene Ther. 2022 Nov;29(11):1662-1675. doi: 10.1038/s41417-022-00485-y. Epub 2022 Jun 8. PubMed PMID: 35676533; PubMed Central PMCID: PMC9663294.

Yang Y, Attwood K, Bshara W, Mohler JL, Guru K, Xu B, Kalinski P, Chatta G. High intratumoral CD8(+) T-cell infiltration is associated with improved survival in prostate cancer patients undergoing radical prostatectomy. Prostate. 2021 Jan;81(1):20-28. doi: 10.1002/pros.24068. Epub 2020 Oct 21. PubMed PMID: 33085799; PubMed Central PMCID: PMC9869431.

Morrison C, Pabla S, Conroy JM, Nesline MK, Glenn ST, Dressman D, Papanicolau-Sengos A, Burgher B, Andreas J, Giamo V, Qin M, Wang Y, Lenzo FL, Omilian A, Bshara W, Zibelman M, Ghatalia P, Dragnev K, Shirai K, Madden KG, Tafe LJ, Shah N, Kasuganti D, de la Cruz-Merino L, Araujo I, Saenger Y, Bogardus M, Villalona-Calero M, Diaz Z, Day R, Eisenberg M, Anderson SM, Puzanov I, Galluzzi L, Gardner M, Ernstoff MS. Predicting response to checkpoint inhibitors in melanoma beyond PD-L1 and mutational burden. J Immunother Cancer. 2018 May 9;6(1):32. doi: 10.1186/s40425-018-0344-8. PubMed PMID: 29743104; PubMed Central PMCID: PMC5944039.

Allott EH, Geradts J, Sun X, Cohen SM, Zirpoli GR, Khoury T, Bshara W, Chen M, Sherman ME, Palmer JR, Ambrosone CB, Olshan AF, Troester MA. Intratumoral heterogeneity as a source of discordance in breast cancer biomarker classification. Breast Cancer Res. 2016 Jun 28;18(1):68. doi: 10.1186/s13058-016-0725-1. PubMed PMID: 27349894; PubMed Central PMCID: PMC4924300.

Sieh W, Köbel M, Longacre TA, Bowtell DD, deFazio A, Goodman MT, Høgdall E, Deen S, Wentzensen N, Moysich KB, Brenton JD, Clarke BA, Menon U, Gilks CB, Kim A, Madore J, Fereday S, George J, Galletta L, Lurie G, Wilkens LR, Carney ME, Thompson PJ, Matsuno RK, Kjær SK, Jensen A, Høgdall C, Kalli KR, Fridley BL, Keeney GL, Vierkant RA, Cunningham JM, Brinton LA, Yang HP, Sherman ME, García-Closas M, Lissowska J, Odunsi K, Morrison C, Lele S, Bshara W, Sucheston L, Jimenez-Linan M, Driver K, Alsop J, Mack M, McGuire V, Rothstein JH, Rosen BP, Bernardini MQ, Mackay H, Oza A, Wozniak EL, Benjamin E, Gentry-Maharaj A, Gayther SA, Tinker AV, Prentice LM, Chow C, Anglesio MS, Johnatty SE, Chenevix-Trench G, Whittemore AS, Pharoah PD, Goode EL, Huntsman DG, Ramus SJ. Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study. Lancet Oncol. 2013 Aug;14(9):853-62. doi: 10.1016/S1470-2045(13)70253-5. Epub 2013 Jul 9. PubMed PMID: 23845225; PubMed Central PMCID: PMC4006367.