Specializing In:
- Clinical epidemiology
- Autologous & allogeneic blood & marrow transplant
- Survivorship
- Data management
Research Interests:
- Genome-wide association studies
- Immunophenotyping by Flow Cytometry
- Social determinants of health
Biography
I have extensive experience conducting clinical outcomes research related to blood and marrow transplantation (BMT). I have over 20 years of experience with inter- and intra-programmatic collaborative clinical and translational research to identify, understand and quantify the risk of adverse outcomes and long-term prognosis in hematologic malignancy patients treated with BMT. My research has investigated outcomes such as graft-versus-host disease, osteoporosis, chemotherapy-associated toxicity, infections and financial burden, as well as the impact of demographic and sociological factors such as age, obesity, place of residence, race, and socioeconomic status, on long-term prognosis after therapy with BMT. I have co-led multi-center, multi-disciplinary projects including:1) recipient and donor genetic susceptibility to transplant-related mortality after unrelated donor BMT, 2) immunophenotyping to detect minimal residual disease in myeloma patients treated on a 3-arm randomized controlled trial, 3) genetic susceptibility to AML, ALL and MDS. I have extensive experience leading and working as part of a variety of multidisciplinary teams on long-term projects involving complex data sources and structures. My teaching experience includes guest lectures on topics spanning ethical conduct of research, clinical epidemiology, blood & marrow transplant, and specific research projects, as well as one-on-one mentoring of students from all levels, including high school, college, graduate school, medical school, residency, clinical and graduate post-doc fellowships.
Positions
Roswell Park Comprehensive Cancer Center
- Professor of Oncology
- Department of Cancer Prevention and Control
Background
Education and Training
- PhD - Epidemiology, State University of New York at Buffalo, Buffalo, NY
- MS - Epidemiology, State University of New York at Buffalo, Buffalo, NY
- BS - Biochemistry from State University of New York at Geneseo, Geneseo, NY
Fellowship
- Hematologic Oncology/Blood and Marrow Transplant (BMT)
Professional Memberships
- American Society of Hematology
- American Society for Blood and Marrow Transplantation
- Center for International Blood and Marrow Transplant Research Registry
Honors & Awards
- 2019 - American Society of Blood and Marrow Transplantation Best Abstract Award
- 2017 - American Society of Blood and Marrow Transplantation Best Abstract Award
- 2006 - National Marrow Donor Program Medical Professional Education Award
- 2005 - American Cancer Society Mentored Research Scholar Award
Publications
Hahn T, Herr M, Brazauskas R, Patel J, Ailawadhi S, Saber W, Khera N. Utilization of hematopoietic cell transplantation for hematologic cancers by race/ethnicity and age. JAMA Network Open 2024, 7(9):e2433145. PMID: 39292462
Herr MM, Balderman SR, Wallace PK, Zhang Y, Tario JD, Buxbaum NP, Holtan S, Ross M, McCarthy PL, Betts B, Maslak P, Hahn TE. Outcomes of human leukocyte antigen-matched related donor and haploidentical allogeneic hematopoietic cell transplantation recipients by immune profiles of recipients and donors. J Transplant Cell Ther 2024, 30(8):808.e1-808.e13. PMID: 38801976
Pasquini MC, Wallace PK, Fraser R, Fei M, Tario JD, Howard A, Zhang Y, Blackwell B, Brunstein C, Efebera Y, Geller N, Giralt S, Hari P, Knust K, Koreth J, Krishnan A, Landau H, Shah N, Somlo G, Stadtmauer E, Vogl DT, Vesole D, McCarthy PL, Hahn T. Minimal residual disease status at 1 year after autologous hematopoietic cell transplantation and lenalidomide maintenance are associated with long-term overall survival. J Clin Oncol 42(23):2757-2768, 2024. PMID: 38701390
Khera N, Ailawadhi S, Brazauskas R, Patel J, Jacobs B, Ustun C, Ballen K, Abid MB, Perez MA, Al-Homsi AS, Hashem H, Hong S, Munker R, Schears RM, Lazarus HM, Ciurea S, Badawy SM, Savani BN, Wirk B, LeMaistre CF, Bhatt NS, Beitinjaneh A, Aljurh M, Sharma A, Cerny J, Knight JM, Kelkar AH, Yared JA, Kindwall-Keller T, Winestone LE, Steinberg A, Arnold SD, Seo S, Preussler JM, Hossain NM, Figrut WB, Agrawal V, Hashmi S, Lehmann LE, Wood WA, Rangarajan HG, Saber W, Hahn T. Trends in volumes and survival after hematopoietic cell transplantation in racial/ethnic minorities. Blood Adv 8(13):3497-3506, 2024. PMID: 38661372
Hahn T, Wang J, Preus LM, Karaesmen E, Rizvi A, Clay-Gilmour AI, Zhu Q, Wang Y, Yan L, Liu S, Stram DO, Pooler L, Sheng X, Haiman CA, van den Berg D, Webb A, Brock G, Spellman SR, Onel K, McCarthy PL, Pasquini MC, Sucheston-Campbell LE. Novel genetic variants associated with mortality after unrelated donor allogeneic hematopoietic cell transplantation. EClinicalMedicine 40: 101093, 2021. PMID: 34746714, PMCID: PMC8548922