Specializing In:
- Clinical epidemiology
- Autologous & allogeneic blood & marrow transplant
- Survivorship
- Data management
Research Interests:
- Genome-wide association studies
- Immunophenotyping by Flow Cytometry
- Blood and Marrow Transplantation
Biography
I have extensive experience conducting clinical outcomes research related to blood and marrow transplantation (BMT). I have over 20 years of experience with inter- and intra-programmatic collaborative clinical and translational research to identify, understand and quantify the risk of adverse outcomes and long-term prognosis in hematologic malignancy patients treated with BMT. My research has investigated outcomes such as graft-versus-host disease, osteoporosis, chemotherapy-associated toxicity, infections and financial burden, as well as the impact of demographic and sociological factors such as age, obesity, place of residence, race, and socioeconomic status, on long-term prognosis after therapy with BMT. I have co-led multi-center, multi-disciplinary projects including:1) recipient and donor genetic susceptibility to transplant-related mortality after unrelated donor BMT, 2) immunophenotyping to detect minimal residual disease in myeloma patients treated on a 3-arm randomized controlled trial, 3) genetic susceptibility to AML, ALL and MDS. I have extensive experience leading and working as part of a variety of multidisciplinary teams on long-term projects involving complex data sources and structures. My teaching experience includes guest lectures on topics spanning ethical conduct of research, clinical epidemiology, blood & marrow transplant, and specific research projects, as well as one-on-one mentoring of students from all levels, including high school, college, graduate school, medical school, residency, clinical and graduate post-doc fellowships.
Positions
Roswell Park Comprehensive Cancer Center
- Professor of Oncology
- Department of Cancer Prevention and Control
Background
Education and Training
- PhD - Epidemiology, State University of New York at Buffalo, Buffalo, NY
- MS - Epidemiology, State University of New York at Buffalo, Buffalo, NY
- BS - Biochemistry from State University of New York at Geneseo, Geneseo, NY
Fellowship
- Hematologic Oncology/Blood and Marrow Transplant (BMT)
Professional Memberships
- American Society of Hematology
- American Society for Blood and Marrow Transplantation
- Center for International Blood and Marrow Transplant Research Registry
Honors & Awards
- 2019 - American Society of Blood and Marrow Transplantation Best Abstract Award
- 2017 - American Society of Blood and Marrow Transplantation Best Abstract Award
- 2006 - National Marrow Donor Program Medical Professional Education Award
- 2005 - American Cancer Society Mentored Research Scholar Award
Publications
Vasu S, Zhao Q, Miller EG, Elder P, Langenberg L, Davies S, Bejanyan N, Hahn T. High incidence of severe TA-TMA increases mortality after allogeneic hematopoietic cell transplant in adults: a prospective MIDAS Consortium study. Blood 146(5):638-46, 2025. PMID: 40300075.
Hahn T, Herr M, Brazauskas R, Patel J, Ailawadhi S, Saber W, Khera N. Utilization of hematopoietic cell transplantation for hematologic cancers by race/ethnicity and age. JAMA Network Open 2024, 7(9):e2433145. PMID: 39292462
Pasquini MC, Wallace PK, Fraser R, Fei M, Tario JD, Howard A, Zhang Y, Blackwell B, Brunstein C, Efebera Y, Geller N, Giralt S, Hari P, Knust K, Koreth J, Krishnan A, Landau H, Shah N, Somlo G, Stadtmauer E, Vogl DT, Vesole D, McCarthy PL, Hahn T *. Minimal residual disease status at 1 year after autologous hematopoietic cell transplantation and lenalidomide maintenance are associated with long-term overall survival. J Clin Oncol 42(23):2757-2768, 2024. PMID: 38701390
Hahn T, Wang J, Preus LM, Karaesmen E, Rizvi A, Clay-Gilmour AI, Zhu Q, Wang Y, Yan L, Liu S, Stram DO, Pooler L, Sheng X, Haiman CA, van den Berg D, Webb A, Brock G, Spellman SR, Onel K, McCarthy PL, Pasquini MC, Sucheston-Campbell LE. Novel genetic variants associated with mortality after unrelated donor allogeneic hematopoietic cell transplantation. EClinicalMedicine 40: 101093, 2021. PMID: 34746714, PMCID: PMC8548922
Zhu Q, Yan L, Liu Q, Zhang C, Hu Q, Preus L, Clay-Gilmour AI, Onel K, Stram DO, Pooler L, Sheng X, Haiman CA, Zhu X, Spellman SR, Pasquini M, McCarthy PL, Liu S, Hahn T *, Sucheston-Campbell LE. Exomechip analyses identify genes affecting mortality after HLA-matched unrelated donor blood and marrow transplantation. Blood 131:2490-99, 2018. PMID: 29610366, PMCID: PMC5981168