Dr. Hu joined the Roswell Park faculty in 2010. He graduated from Peking University with a degree in medicine and received his PhD in Bioinformatics from Tsinghua University. He is skilled in PERL and R computing languages, and has extensive experience in utilizing parallel computing in high-performance servers to process, analyze and interpret high-dimension, high-complexity data. An example of a recently developed tool is VPA (Hu et al. BMC Research Note. 2012; 5:31 PMC3293055), which is a customized package for analyzing variants with user-specified frequency pattern from NGS studies.
Waight JD, Hu Q, Miller A, Liu S, Abrams SI. Tumor-derived G-CSF facilitates neoplastic growth through a granulocytic myeloid-derived suppressor cell-dependent mechanism. PloS One 2011; 6(11):e27690
Hu Q, Wang D, Yan L, Zhao H, Liu S. VPA: an R tool for analyzing sequencing variants with user-specified frequency pattern. BMC Research Notes 2012; 5:31
Mannava S, Zhuang D, Nair JR, Bansal R, Wawrzyniak JA, Zucker SN, Fink EE, Moparthy KC, Hu Q, Liu S, Boise LH, Lee KP, Nikiforov MA. KLF9 is a novel transcriptional regulator of bortezomib- and LBH589-induced apoptosis in multiple myeloma cells. Blood 2012; 119(6):1450-1458
Shen J, Wang D, Gregory SR, Medico L, Hu Q, Yan L, Odunsi K, Lele SB, Ambrosone CB, Liu S, Zhao H. Evaluation of microRNA expression profiles and their associations with risk alleles in lymphoblastoid cell lines of familial ovarian cancer. Carcinogenesis 2012; 33(3):604-612
Wang D, Yan L, Hu Q, Sucheston LE, Higgins MJ, Ambrosone CB, Johnson CS, Smiraglia DJ, Liu S. IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data. Bioinformatics (Oxford, England) 2012; 28(5):729-730
Heller ER, Gor A, Wang D, Hu Q, Katdare M, Liu S, Sinha AA. Transcriptomal analysis in basal cell carcinoma provides insights into the genetic basis of disease. Journal of Investigative Dermatology 2012; 132(Suppl. 1):S23