Specializing In:
- Clinical cancer epidemiology
Research Interests:
- Elucidate etiology of second cancers
- Treatment-related toxicities/late-effects
- Health disparities
- Survivorship care with a particular focus on lung and breast cancer
Biography
After completing my initial education in Medicine, Behavioral Sciences and Cancer epidemiology, I decided to advance my training in clinical cancer research by joining as a postdoctoral research fellow in the Radiation Epidemiology Branch in the Division of Cancer Epidemiology and Genetics within the National Cancer Institute (NCI). During this period (2017 to 2021), I focused my research on understanding the etiology of second cancers.
I joined Roswell Park Comprehensive Cancer Center in 2022 as an Assistant Professor of Oncology. Presently, I am housed in the Department of Thoracic Surgery and have a secondary appointment with Cancer Prevention and Population Sciences.
Positions
Roswell Park Comprehensive Cancer Center
- Assistant Professor of Oncology
- Department of Thoracic Surgery
- Assistant Member, Cancer Center Support Grant
- Department of Cancer Prevention and Control
Background
Education and Training
- 2011-2016 - DrPH - Health Promotion and Behavioral Sciences, Cancer Epidemiology, The University of Texas, Health Science Center, School of Public Health, Houston, TX
- 2004-2008 - MD, American Institute of Medicine, Seychelles
- 2009 -2011 - MPH - Health Education, Leadership Sciences, Western Kentucky University, Bowling Green, KY
Fellowship
- 2017-2021 - Post-doctoral Research fellowship, Cancer Research Training Award (CRTA) Fellow, Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD
- 2016-2017 - Post-doctoral fellowship, Division of Radiation Oncology, MD Anderson Cancer Center, Houston, TX
- 2015-2016 - Susan G. Komen pre-doctoral fellowship, Graduate Training Program in Breast Cancer Disparities, Department of Health Promotion and Behavioral Sciences, Houston, TX
Professional Memberships
- American Association for Cancer Research
- American Society of Clinical Oncology
- Radiation Research Society
- International Society of Radiation Epidemiology and Dosimetry
Honors & Awards
- 2020 - Diversity Career Development Program award, NCI, NIH
- 2019 - Fellows Award for Research Excellence 2020, NCI, NIH
- 2016 - Outstanding Contribution in Public Health, National Delta Omega Honorary Society in Public Health, Alpha Iota Chapter, Texas
- 2015 - Jon Shevell Young Scientist Scholarship, Susan G. Komen Foundation, TX
- 2015 - Scholar-in-Training Award, American Association for Cancer Research, Atlanta, GA
- 2014 - Beth Sanders Moore Scholarship in Public Health, UT School of Public Health
- 2014 - Gerry C. Gunnin, Ph.D. Public Health Memorial Scholarship, Texas Health, Texas
- 2013 - Most Outstanding Research Award, American Association for Cancer Research, Washington, DC
- 2013 - Scholar-in-Training Award, American Association for Cancer Research, Washington, DC
Research Overview
The dramatic advances in diagnostic and therapeutic aspects of cancer management over the recent decades and the resulting improved survival among cancer patients have contributed to a rapidly increasing number of cancer survivors in the United States. These patients, however, are vulnerable to several early- and late-effects including adverse events from cancer treatments, as well as serious concerns such as disease recurrences and/or second primary malignancies. Second primary malignancies, or “second cancers,” are a leading cause of morbidity and mortality among survivors. The overarching objective of my research program is to quantify the risk of second cancers among various populations of cancer survivors. Through my efforts, I hope to impact the clinical practice of cancer care by informing risk-benefit assessment of various treatment approaches and long-term surveillance guidelines while contributing to our understanding of second cancer etiology.
Additionally, through my experience in cancer research over the past years, I have observed differences in receipt of cancer care, as certain groups tend to bear a disproportionate burden of cancer, and these cancer-related late effects, relative to other groups. Therefore, I also investigate disparities in adherence to cancer treatment and survivorship care and study the role of various demographic and clinical factors in treatment-related decisions and resulting health outcomes. The eventual goal of my research is to generate results in the field of oncology that can motivate and justify evidence-based investment to reduce cancer-related health disparities and inform cancer control strategies towards both, first primary, and second primary malignancies.
Publications
1. Morton LM, Curtis RE, Linet MS, Schonfeld SJ, Advani PG, Dalal NH, Sasse EC, Dores GM. Trends in Risk for Therapy-Related Myelodysplastic Syndrome/Acute Myeloid Leukemia After Initial Chemo/Immunotherapy for Common and Rare Lymphoid Neoplasms, 2000-2018. Article (Original Research). In collaboration with investigators at Division of Cancer Epidemiology and Human Genetics at the NCI. Accepted in eClinicalMedicine, The Lancet Discovery Science. June 2023.
2. Pithadia K, Advani PG, Schonfeld S, Withrow D, Bekelman J, Citrin D, Berrington De Gonzalez A, Morton LM. Comparing Risk for Second Primary Cancers After Intensity-Modulated vs 3-Dimensional Conformal Radiation Therapy for Prostate Cancer, 2002-2015. JAMA Oncology. May 2023
3. Advani PG, Morton LM, Kitahara CM, Berrington-Gonzalez A, Ramin C, Haymart MR, Curtis RE, Schonfeld SJ. Assessment of surveillance bias versus etiologic factors in the reciprocal association between papillary thyroid cancer and breast cancer. Cancer Epidemiology. July 2021
4. Advani PG, Advani SM; Parelkar P; VonVille H; Diamond P, Burnett J, Brewster AM, Vernon SW. Racial/ethnic disparities in use of surveillance mammogram among breast cancer survivors: A systematic review study. The Journal of Cancer Survivorship. May 2021
5. Advani PG, Schonfeld SJ, Curtis RE, Dores GM, Linet MS, Sigel BS, Lam CJK, Tucker MA, Chanock SJ, Morton LM. Risk of therapy-related myelodysplastic syndrome/acute myeloid leukemia after childhood cancer: a population-based study. Leukemia. April 2019.