Latif Kazim


About Latif Kazim


Roswell Park Comprehensive Cancer Center
  • Emeritus Faculty
  • Cell Stress Biology


Education and Training:

  • 1979-1981 - Postdoctoral, Immunology, Mayo Graduate School, Rochester, MN
  • PhD - University of Minnesota/Mayo Graduate School, Rochester, MN
  • 1974 - MA - Biochemistry, Wayne State University, Detroit, MI
  • 1971 - BA - Chemistry/Biology, Boston University, Boston, MA


  • Arnouk H, Zynda ER, Wang X-Y, Hylander BL, Manjili MH, Repasky EA, Subjeck JR, Latif Kazim A. Tumour secreted grp170 chaperones full-length protein substrates and induces an adaptive anti-tumour immune response in vivo. International journal of hyperthermia 2010; 26(4):366-375
  • Jones MB, Nasirikenari M, Feng L, Migliore MT, Choi K-S, Kazim L, Lau JTY.Role for hepatic and circulatory ST6Gal-1 sialyltransferase in regulating myelopoiesis. Journal of biological chemistry 2010; 285(32):25009-25017
  • Kunapuli P, Jang G-F, Kazim L, Cowell JK. Mass spectrometry identifies LGI1-interacting proteins that are involved in synaptic vesicle function in the human brain. Journal of molecular neuroscience : MN 2009; 39(1-2):137-143
  • Prieto Conaway M, Cao S, Durrani F, Rustum Y, Wang P, Marlar K, Kazim L. Using mass spectrometry for tissue imaging. Genetic engineering and biotechnology news 2009; 29(11):34-35
  • Sternberg Z, Weinstock-Guttman B, Leung C, Chadha K, Benedict RHB, Kazim L, Bistulfi GL, Sternberg D, Hennies C, Munschauer F. Plasma pentosidine: a potential biomarker in the management of multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England) 2011; 17(2):157-163
  • Toor AA, Kazim L, Detwiler M, McCarty JM, Clark WB, Veronica B, Chung HM, Idowu M, Sabo R, Roberts CH, Mallory KL, Berrie JL, Kmieciak M, Manjili MH.Distinct oligoclonal T cells are associated with GVHD or GVHD -free responses in patients with hematologic malignancies following stem cell transplantation. Biology of blood and marrow transplantation 2011; 17(Suppl. 2):491
  • Sternberg Z, Grazioli E, Rocco P, Drake A, Kazim L, Lieberman A, Chadha K, Zivadinov R, Zamboni P, Hojnacki D, Weinstock-Guttman B, Munschauer F.Soluble receptor for advanced glycation end products in multiple sclerosis: a potential marker of disease severity. Multiple sclerosis (Houndmills, Basingstoke, England) 2008; 14(6):759-763
  • Beachy SH, Kisailus AJ, Repasky EA, Subjeck JR, Wang XY, Kazim AL.Engineering secretable forms of chaperones for immune modulation and vaccine development. Methods (San Diego, Calif.) 2007; 43(3):184-193
  • Sharma S, Tammela J, Wang X, Arnouk H, Driscoll D, Mhawech-Fauceglia P, Lele S, Kazim AL, Odunsi K. Characterization of a putative ovarian oncogene, elongation factor 1alpha, isolated by panning a synthetic phage display single-chain variable fragment library with cultured human ovarian cancer cells. Clinical cancer research 2007; 13(19):5889-5896
  • Geng F, Tang L, Li Y, Yang L, Choi K-S, Kazim AL, Zhang Y. Allyl isothiocyanate arrests cancer cells in mitosis, and mitotic arrest in turn leads to apoptosis via Bcl-2 protein phosphorylation. Journal of biological chemistry2011; 286(37):32259-32267
  • Migliore MT, Choi KS, Kazim AL, Lau JTY, Jones MB. Ablating the ST6Gal-1 Hepatic Promoter Alters the alpha 2,6-Sialylation Pattern of Serum Glycoproteins but not the Overall Degree of Sialylation. Glycobiology 2008;18(11):109
  • Sternberg Z, Weinstock-Guttman B, Chadha K, Lieberman A, Hojnacki D, Zamboni P, Zivadinov R, Kazim L, Drake AS, Grazioli E, Munschauer FE.sRAGE: A potential biomarker of multiple sclerosis disease severity. Multiple sclerosis (Houndmills, Basingstoke, England) 2008; 14(Suppl. 1):S245
  • Bu Y, Smolinski M, Qu J, Kazim L, Gelman I, Dyster L, Hangauer D.Mechanism of action KX01 (KX2-391), a novel tubulin polymerization and Src signaling inhibitor proceeding to Phase II clinical trials . Proceedings of the American Association for Cancer Research Annual Meeting 2010; 51:Abstract #2487
  • Conaway MCP, Cao S, Durrani F, Rustum Y, Wang P, Marlar K, Kazim L. The role of MALDI-enabled linear ion trap mass spectrometry as a sensitive tool in tissue imaging. Spectroscopy Europe 2008; 20(6):12-14
  • Berrie JL, Kmieciak M, Sabo RT, Roberts CH, Idowu MO, Mallory K, Chung HM, McCarty JM, Borrelli CA, Detwiler MM, Kazim AL, Toor AA, Manjili MH.Distinct oligoclonal T cells are associated with graft versus host disease after stem-cell transplantation. Transplantation 2012; 93(9):949-957
  • George S, Choi K-S, Pili R, Kazim AL. The lipid metabolome of clear cell renal cell carcinoma (CCRCC). Journal of clinical oncology 2012; 30(15 Suppl.):Abstract #10609