Gregory Freund

Anatomic Pathology

Specializing In:


About Gregory Freund


After receiving my BA in Studio Art from Wesleyan University, I went on to study medicine and pathology at the University of Rochester. Currently, I am the Chief of Cytopathology at Roswell Park Comprehensive Cancer Center. As a cytopathologist, I examine cells microscopically to determine if they have morphologic features consistent with malignancy. I am also a physician-scientist who has investigated the neuroimmune consequences of anxiety and depressive disorders for nearly three decades. I am particularly interested in the role of anxiety in neuroimmune dysregulation and the development of molecular-based countermeasures to protect against stress-associated carcinogenesis.


Roswell Park Comprehensive Cancer Center
  • Professor of Oncology, Pathology, Cytopathology
  • Department of Pathology


Education and Training:

  • 1983-1988 - MD - University of Rochester, Rochester, NY


  • 1988-1993 - Pathology, University of Rochester Medical Center, Rochester, NY


  • 1992-1994 - Research Fellow, Wilmot Cancer Institute, University of Rochester, Rochester, NY

Board Certification:

  • 1993 - American Board of Pathology, Anatomic and Clinical Pathology
  • 1997 - American Board of Pathology, Cytopathology

Professional Memberships:

  • American Society of Cytopathology (ASC)
  • American Society of Clinical Pathologists (ASCP)
  • Association of Pathology Chairs (APC)


Gainey, S.J., Horn, G.P., Towers, A.E., Oelschlager, M.L., Tir, V.L., Drnevich, J., Fent, K.W., Kerber, S., Smith, D.L., Freund, G.G. (2018) Exposure to a firefighting overhaul environment without respiratory protection increases immune dysregulation and lung disease risk. Plos One. 13:e0201830

Juda, M.B., Brooks, A.K., Towers, A.E., Freund, G.G., McCusker, R.H., Steelman, A.J (2019) Indoleamine 2,3-dioxygenase 1 deletion promotes Theiler's virus-induced seizures in C57BL/6J mice. Epilepsia. 60:626-635

Towers, A.E., Oelschlager, M.L., Lorenz, M., Gainey, S.J., McCusker, R.H., Krauklis, S.A., Freund, G.G. (2019) Handling stress impairs learning through a mechanism involving caspase-1 activation and adenosine signaling. Brain Behavior and Immunity. 80:763-776

Towers, A.E., Freund, G.G. (2019) Nutritional psychoneuroimmunology: is the inflammasome a critical convergence point for stress and nutritional dysregulation? Current Opinion in Behavioral Sciences. 28:20-24

Towers, A.E., Oelschlager, M.L., Juda, M.B., Jain, S., Gainey, S.J,. Freund, G.G. (2020) HFD refeeding in mice after fasting impairs learning by activating caspase-1 in the brain. Metabolism. 102:153989