Roswell Park at ASH

Sunday, December 7th, 2025

• Meredith Stone, PhD, is presenting author, with senior author Marco Davila, MD, PhD, presenting  abstract 13711 — CAR T cell-driven induction of iNOS in tumor associated macrophages promotes CAR T cell resistance in B cell lymphoma.

Monday, December 8th, 2025

• Eunice Wang, MD, is senior author presenting abstract 7396 – Crenolanib plus salvage chemotherapy improves outcomes in FLT3-mutant and NPM1 co-mutated relapsed/refractory (R/R) acute myeloid leukemia (AML): Results from a randomized, placebo-controlled, double-blind trial; presenting author is Thomas Cluzeau, MD, PhD, of Centre Hospitalier Universitaire de Nice.
• Eunice Wang, MD, is senior author presenting abstract 3910 – Ziftomenib in combination with venetoclax and azacitidine in relapsed/refractory NPM1-m or KMT2A-r acute myeloid leukemia: Updated phase 1a/b safety and clinical activity results from KOMET007; presenting author is Amir Fathi, MD, of Massachusetts General Hospital/Dana-Farber Harvard Cancer Center.
• Megan Herr, PhD, is presenting author with senior author Theresa Hahn, PhD, presenting  abstract 8885 – Overall survival after post-transplant cyclophosphamide (PTCy) peripheral blood hematopoietic cell transplantation (HCT) differs by race, ethnicity, and donor.

Saturday, December 6th, 2025

• Ehsan Malek, MD, is first/presenting author on abstract 11278 – Unstructured serum electrophoresis data limits real-world AI models in multiple myeloma: Evaluation of 384 institutions across United States.
• Ehsan Malek, MD, is first/presenting author on abstract 11347 – Race agnostic models maintain accuracy in predicting m-protein levels in multiple myeloma.
• Theresa Hahn, PhD, is first/presenting author on abstract 11153 – Pre-HCT creatinine defines sex-specific risk for severe TMA after allogeneic transplantation: A report from the MIDAS consortium.
• Jens Hillengass, MD, PhD, is senior/presenting author, with first author Janine Joseph, MS, MBA, on abstract 14670 – Peripheral blood and bone marrow immune profiles are strongly correlated in patients with plasma cell disorders.
• Ross McCauley, MD, is first/presenting author on abstract 13552 – CRS/ICANS prophylaxis does not improve outcomes in adult patients with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL) treated with brexucabtagene autoleucel.
• Murugan Selvam, PhD, is first/presenting author, with senior author Pamela Sung, MD, PhD, on abstract 1911 – Combined FLT3 and EZH1/2 inhibition reduces LSCs and promoted myeloid differentiation in PDX models of AML.
• Rabsa Sikder is first author, with senior author Song Yao, MD, PhD, on abstract 1544 – Age at diagnosis drives molecular pathology and prognosis in diffuse large B-cell lymphoma.

Sunday, December 7th, 2025

• Anuja Abhyankar, MD, is senior/presenting author on abstract 12420 – Real-world comparative effectiveness of quadruplet vs. triplet induction in multiple myeloma.
• Marco Davila, MD, PhD, is senior/presenting author, with first author Brian Betts, MD, on abstract 1897 – CD83 CAR T overcome CD19 antigen loss in B-cell malignancies after CD19-directed therapy.
• Marco Davila, MD, PhD, is senior/presenting author, with first author Min Ma, MD, on abstract 2219 – In-depth, quantitative characterization of important regulators and predictive biomarkers for CAR T-cell therapy induced toxicities in a clinical cohort.
• Ehsan Malek, MD, is first/presenting author on abstract 11165 – Accelerated immune aging after induction therapy in multiple myeloma revealed by donor-referenced immune age modeling.
• Ehsan Malek, MD, is senior/presenting author, with first author Rahul Thakur, MD, on abstract 4075 – Peripheral circulating myeloma cells accurately identify bone marrow MRD positivity in multiple myeloma patients receiving CAR T or autologous transplant.
• Leslie Martinez-Gutierrez, MS, is first/presenting author, with senior author Eunice Wang, MD, on abstract 9762 – PARP inhibition by talazoparib results in leukemia cell death via induction of myeloid differentiation.
• Nour Nassour, MD, is first/presenting author, with co-senior authors Philip McCarthy, MD, and Hemn Mohammadpour, DVM, PhD, on abstract 7910 – Galectin-3 in host murine models lessens severity of graft-versus-host disease by preserving intestinal stem cells irrespective of gut microbiota composition.
• Alex Niu, MD, is first/presenting author, with senior author Francisco Hernandez-Ilizaliturri, MD, on abstract 9628 – Evaluation of outcomes and toxicities of loncastuximab tesirine (Lonca) in relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL): Real-world data analysis (RWDA) from 10 US academic centers.
• Rahul Thakur, MD, is first/presenting author, with senior authors Francisco Hernandez-Ilizaliturri, MD, and Alex Niu, MD, on abstract 7358 – Polatuzumab vedotin in combination with rituximab, cyclophosphamide, doxorubicin and prednisone (Pola R+CHP) results in similar clinical outcomes than rituximab and dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, and doxorubucin (R+DA+EPOCH) in patients with high-risk features diffuse large B-cell lymphoma (DLBCL).
• Eunice Wang, MD, is senior/presenting author on abstract 2246 – Analysis of hematologic improvement (HI) by time to response in relapsed/refractory acute myeloid leukemia (AML) patients treated with olutasidenib.

Monday, December 8th, 2025

• Sawyer Bawek, MD, is first/presenting author, with co-senior authors Megan Herr, PhD, and Jens Hillengass, MD, PhD, on abstract 14319 – Impact of pre-transplant functional status and comorbidities on outcomes in individuals with multiple myeloma undergoing autologous hematopoietic cell transplantation.
• Elizabeth Bouchard, PhD, MA, is first/presenting author, with senior author Kara Kelly, MD, on abstract 4618 – Advancing strategies to improve chemotherapy adherence in young children with ALL: Understanding the role of behavioral parenting skills and daily barriers to identify novel intervention targets.
• Ajinkya Buradkar, MD, is first/presenting author and Francisco Hernandez-Ilizaliturri, MD, is senior author on abstract 15602 – Impact of apheresis-to-infusion interval on outcomes and toxicity of CAR T therapy in relapsed/refractory DLBCL.
• Philip McCarthy, MD, is presenting author, with first author Janine Joseph, MS, MBA, and senior author Jens Hillengass, MD, PhD, on abstract 14567 – Circulating immune profile in patients with amyloidosis.
• Allan Pavy, PhD, is first/presenting author, with senior author Marco Davila, MD, PhD, on abstract 7239 – IL-2 mutein-mediated improvement of CAR T function in relapsed/refractory diffuse B-Cell lymphoma.
• Rahul Thakur, MD, is first/presenting author, with senior author Eunice Wang, MD, on abstract 4133 – Machine learning accurately predicts mortality in adult NPM1-mutant acute myeloid leukemia using baseline clinical and genomic features.
• Jacob Wright is first/presenting author, with senior authors Matthew Cortese, MD, MPH, and Spencer Rosario, PhD, on abstract 5661 – Multiomic correlates of ex vivo αCD19 chimeric antigen receptor T-cell (CAR T) cytotoxicity in venetoclax-treated patients with chronic lymphocytic leukemia (CLL).
• Eunice Wang, MD, is first/presenting author on abstract 5221 – Favorable Outcomes Including Post-Transplant Survival Are Seen Independent of Baseline Skin Burden in Treatment-Naϊve Patients (Pts) with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Treated with Tagraxofusp (TAG): Subgroup Analysis of a Pivotal Trial.

Roswell Park moderator roles

• Ehsan Malek, MD, will moderate oral abstract session 907 – Outcomes Research: Plasma Cell Disorders: Innovations in Myeloma: Therapy, Prevention & Patient-Centered Care.
• Rohit Gosain, MD, will co-host Advancements in Oncology – Today’s Data for Tomorrow’s Practice.
• Pamela Sung, MD, PhD, will moderate oral abstract session 604 – Molecular Pharmacology and Drug Resistance: Myeloid Neoplasms - Novel Targets and Drugs.
• Eunice Wang, MD, will be the featured speaker at an educational session, The Promise of Menin Inhibitors: From Approval to Triplet Regimens.

Awards and recognitions

Six experts representing Roswell Park and the University at Buffalo Jacobs School of Medicine and Biomedical Sciences earned ASH abstract Achievement Awards for work to be presented during the meeting:

• Nour Nassour, MD,  
• Anuja Abhyankar, MD,
• Ross McCauley, MD,
• Allan Pavy, PhD,
• Rahul Thakur, MD,
• Jacob Wright (Predoctoral trainee)