Elizabeth Griffiths, MD

Elizabeth Griffiths, MD

Associate Professor of Oncology
Leukemia Service
Department of Medicine
Roswell Park Cancer Institute
Clinical Assistant Professor
Department of Medicine
Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo
Areas of Expertise: 
Acute lymphoblastic leukemia (ALL)
Acute myeloid leukemia (AML)
Chronic myeloid leukemia (CML)
Hematologic Oncology
Myelodysplastic syndrome (MDS)
Myeloproliferative diseases (MPD)
Special Interests: 
Epigenetic changes in leukemia and myelodysplastic syndromes, novel therapeutics for elderly Acute Myeloid Leukemia


Elizabeth Griffiths, MD, joined Roswell Park’s Leukemia Service in the Department of Medicine in March 2010. Dr. Griffiths treats patients with blood disorders, specifically acute myeloid and lymphoid leukemias as well as bone marrow failure syndromes such as aplastic anemia and myelodysplastic syndrome. The program in myelodysplasia at RPCI is recognized by the MDS Foundation as an MDS Center of Excellence. She is a Clinical Assistant Professor at the State University of New York (SUNY) at Buffalo and is a faculty member of the Roswell Park Cancer Institute-SUNY Buffalo graduate training programs in the departments of Pharmacology and Therapeutics as well as Immunology.

She joined RPCI following completion of a five-year medical oncology and hematology fellowship at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital in Baltimore, MD. She had previously completed her internal medicine residency, also at Johns Hopkins, in 2005. Dr. Griffiths graduated with honors in 2002, earning her degree as Doctor of Medicine with Distinction from the University of North Carolina School of Medicine, Chapel Hill.

Dr. Griffiths is board certified in hematology, oncology and internal medicine and is licensed in both New York and Maryland. Dr. Griffith’s is a member of multiple professional organizations, including the American Society of Hematology, the American Association for Cancer Research, and the American Society of Oncology.

Her research focuses on the mechanism of action of hypomethylating drugs (HMAs), specifically the contribution of the immune system to these responses. Her research examines the potential contribution of re-expressed Cancer-Germline antigens to the induction of anti-leukemic immune responses, as well as the direct impact on T-cell subsets in patients with myeloid malignancy following exposure to HMAs. She has authored or co-authored over 20 peer-reviewed publications.


Education and Training: 
2002 - University of North Carolina School of Medicine, Chapel Hill, NC
2005 - Internal Medicine - Johns Hopkins Hospital, Baltimore, MD
2010 - Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, Baltimore, MD
Board Certification: 
2008 - Hematology - American Board of Internal Medicine
2009 - Oncology - American Board of Internal Medicine
2005 - Internal Medicine - American Board of Internal Medicine