You’ll find groundbreaking research from the Shafirstein Lab in many peer-reviewed oncology and scientific journals.
Computational Optimization of Irradiance and Fluence for Interstitial Photodynamic Therapy Treatment of Patients with Malignant Central Airway Obstruction
- Journal: Cancers (Basel), May 2023
- Authors: Oakley E, Parilov E, Beeson K, Potasek M, Ivanick N, Tworek L, Hutson A, Shafirstein G.
- Citation: Cancers (Basel). 2023 May 6;15(9):2636
First-In-Human Computer-Optimized Endobronchial Ultrasound-Guided Interstitial Photodynamic Therapy for Patients with Extrabronchial or Endobronchial Obstructing Malignancies
- Journal: JTO Clinical and Research Reports, June 2022
- Authors: Ivanick NM, Oakley ER, Kunadharaju R, Brackett C, Bellnier DA, Tworek LM, Kurenov SN, Gollnick SO, Hutson AD, Busch TM, Shafirstein G.
- Citation: JTO Clin Res Rep. 2022 Jun 26;3(10):100372
- Mudambi S, et al. KDM1A inhibition increases UVA toxicity and enhances photodynamic therapy efficacy. Photodermatol Photoimmunol Photomed. 2023 May;39(3):226-234. doi: 10.1111/phpp.12826.
- Ledezma DK, et al. Interstitial Photothermal Therapy Generates Durable Treatment Responses in Neuroblastoma. Adv Healthc Mater. 2022 Oct;11(20):e2201084. doi: 10.1002/adhm.202201084.
- Shafirstein G, et al. In Vivo Models for Studying Interstitial Photodynamic Therapy of Locally Advanced Cancer. Methods Mol Biol. 2022;2451:151-162. doi: 10.1007/978-1-0716-2099-1_11.
- Bair KL, et al. In vitro Photodynamic Therapy of Polymicrobial Biofilms Commonly Associated With Otitis Media. Front Microbiol. 2020 Aug 31;11:558482. doi: 10.3389/fmicb.2020.558482.
- Luke-Marshall NR, et al. Antimicrobial Photodynamic Therapy with Chlorin e6 Is Bactericidal against Biofilms of the Primary Human Otopathogens. mSphere. 2020 Jul 15;5(4):e00492-20. doi: 10.1128/mSphere.00492-20.
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Clinical trialChamberlain S, et al. TLD1433-Mediated Photodynamic Therapy with an Optical Surface Applicator in the Treatment of Lung Cancer Cells In Vitro. Pharmaceuticals (Basel). 2020 Jun 28;13(7):137. doi: 10.3390/ph13070137.
Light Dosimetry for Photodynamic Therapy with Porfimer Sodium in Treating Participants with Malignant Mesothelioma or Non-Small Cell Lung Cancer with Pleural Disease Undergoing Surgery
See the science
Press release - Oakley E, et al. Irradiance, Photofrin® Dose and Initial Tumor Volume are Key Predictors of Response to Interstitial Photodynamic Therapy of Locally Advanced Cancers in Translational Models. Photochem Photobiol. 2020 Mar;96(2):397-404. doi: 10.1111/php.13207.
- Chamberlain S, et al. An Optical Surface Applicator for Intraoperative Photodynamic Therapy. Lasers Surg Med. 2020 Jul;52(6):523-529. doi: 10.1002/lsm.23168. Epub 2019 Oct 6.
- Shafirstein G, et al. Irradiance controls photodynamic efficacy and tissue heating in experimental tumours: implication for interstitial PDT of locally advanced cancer. Br J Cancer. 2018 Nov;119(10):1191-1199. doi: 10.1038/s41416-018-0210-y.
- Han Y, et al. Reconstruction of a Deformed Tumor Based on Fiducial Marker Registration: A Computational Feasibility Study. Technol Cancer Res Treat. 2018 Jan 1;17:1533034618766792. doi: 10.1177/1533034618766792.
- Bagati A, et al. FOXQ1 controls the induced differentiation of melanocytic cells. Cell Death Differ. 2018 Jun;25(6):1040-1049. doi: 10.1038/s41418-018-0066-y.
- Harris K, et al. Endobronchial ultrasound-guidance for interstitial photodynamic therapy of locally advanced lung cancer-a new interventional concept. J Thorac Dis. 2017 Aug;9(8):2613-2618. doi: 10.21037/jtd.2017.07.45.
- Shafirstein G, et al. Interstitial Photodynamic Therapy-A Focused Review. Cancers (Basel). 2017 Jan 24;9(2):12. doi: 10.3390/cancers9020012.
Contact the Shafirstein Lab
Email: Gal.Shafirstein@RoswellPark.org
Phone: 716-845-4025
Department of Cell Stress Biology
Roswell Park Comprehensive Cancer Center
Elm and Carlton Streets
Buffalo, NY 14263