Research from the Nemeth Lab has been published in numerous influential journals in the fields of hematology, endocrinology and immunotherapy.
Inhibiting the biogenesis of myeloid-derived suppressor cells enhances immunotherapy efficacy against mammary tumor progression
- Journal: Journal of Clinical Investigaition, December 2022
- Authors: Colligan SH, Amitrano AM, Zollo RA, Peresie J, Kramer ED, Morreale B, Barbi J, Singh PK, Yu H, Wang J, Opyrchal M, Sykes DB, Nemeth MJ, Abrams SI.
- Citation: J Clin Invest. 2022 Dec 1;132(23):e158661. doi: 10.1172/JCI158661.
- Bellusci L, et al. Neutralization of SARS-CoV-2 Omicron after vaccination of patients with myelodysplastic syndromes or acute myeloid leukemia. Blood. 2022 May 5;139(18):2842-2846. doi: 10.1182/blood.2022016087. PMID: 35344579; PMCID: PMC8964006.
- Lightman SM, et al. Indoleamine 2,3-dioxygenase 1 is essential for sustaining durable antibody responses. Immunity. 2021 Dec 14;54(12):2772-2783.e5. doi: 10.1016/j.immuni.2021.10.005. Epub 2021 Nov 16. PMID: 34788602; PMCID: PMC9323746.
- Ngai LL, et al. Bimodal expression of potential drug target CLL-1 (CLEC12A) on CD34+ blasts of AML patients. Eur J Haematol. 2021 Sep;107(3):343-353. doi: 10.1111/ejh.13672. Epub 2021 Jun 26. PMID: 34053123; PMCID: PMC8457079.
- Srivastava P, et al. Inhibition of LSD1 in MDS progenitors restores differentiation of CD141Hi conventional dendritic cells. Leukemia. 2020 Sep;34(9):2460-2472. doi: 10.1038/s41375-020-0765-5. Epub 2020 Feb 25. PMID: 32099035; PMCID: PMC7483249.
- Twum DY, et al. IFN regulatory factor-8 expression in macrophages governs an antimetastatic program. JCI Insight. 2019 Feb 7;4(3):e124267. doi: 10.1172/jci.insight.124267. PMID: 30728331; PMCID: PMC6413790.
- Elahi S, et al. The RNA binding protein Ars2 supports hematopoiesis at multiple levels. Exp Hematol. 2018 Aug;64:45-58.e9. doi: 10.1016/j.exphem.2018.05.001. Epub 2018 May 15. PMID: 29775646; PMCID: PMC6103522.
- Griffiths EA, et al. NY-ESO-1 Vaccination in Combination with Decitabine Induces Antigen-Specific T-lymphocyte Responses in Patients with Myelodysplastic Syndrome. Clin Cancer Res. 2018 Mar 1;24(5):1019-1029. doi: 10.1158/1078-0432.CCR-17-1792. Epub 2017 Sep 25. PMID: 28947565; PMCID: PMC5844797.
- Mayer B, et al. Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia. Sci Transl Med. 2017 Nov 29;9(418):eaao1632. doi: 10.1126/scitranslmed.aao1632. PMID: 29187641; PMCID: PMC6309406.
- Bagati A, et al. Melanoma Suppressor Functions of the Carcinoma Oncogene FOXQ1. Cell Rep. 2017 Sep 19;20(12):2820-2832. doi: 10.1016/j.celrep.2017.08.057. PMID: 28930679; PMCID: PMC5664207.
- Dougher CWL, et al. The blood-borne sialyltransferase ST6Gal-1 is a negative systemic regulator of granulopoiesis. J Leukoc Biol. 2017 Aug;102(2):507-516. doi: 10.1189/jlb.3A1216-538RR. Epub 2017 May 26. PMID: 28550122; PMCID: PMC5505748.
- Netherby CS, et al. The Granulocyte Progenitor Stage Is a Key Target of IRF8-Mediated Regulation of Myeloid-Derived Suppressor Cell Production. J Immunol. 2017 May 15;198(10):4129-4139. doi: 10.4049/jimmunol.1601722. Epub 2017 Mar 29. PMID: 28356386; PMCID: PMC5450940.
Connect with the Nemeth Lab
Email: Michael.Nemeth@RoswellPark.org
Phone: 716-845-1775
Department of Immunology
Roswell Park Comprehensive Cancer Center
Elm and Carlton Streets
Buffalo, NY 14263