Buxbaum Lab Publications

In vivo deuterium magnetic resonance imaging of xenografted tumors following systemic administration of deuterated water

• Journal: Scientific Reports, September 2023
• Authors: Brender JR, Assmann JC, Farthing DE, Saito K, Kishimoto S, Warrick KA, Maglakelidze N, Larus TL, Merkle H, Gress RE, Krishna MC, Buxbaum NP
• Citation: Sci Rep. 2023 Sep 7;13(1):14699. doi: 10.1038/s41598-023-41163-9.

Targeting of chimeric antigen receptor T cell metabolism to improve therapeutic outcomes

• Journal: Frontiers in Immunology, March 2023
• Authors: Nanjireddy PM, Olejniczak SH, Buxbaum NP
• Citation: Front Immunol. 2023 Mar 14;14:1121565. doi: 10.3389/fimmu.2023.1121565.

Chronic GvHD NIH Consensus Project Biology Task Force: evolving path to personalized treatment of chronic GvHD

• Journal: Blood Advances, September 2023
• Authors: Buxbaum NP, Socié G, Hill GR, MacDonald KPA, Tkachev V, Teshima T, Lee SJ, Ritz J, Sarantopoulos S, Luznik L, Zeng D, Paczesny S, Martin PJ, Pavletic SZ, Schultz KR, Blazar BR
• Citation: Blood Adv. 2023 Sep 12;7(17):4886-4902. doi: 10.1182/bloodadvances.2022007611.

Is It Possible to Separate the Graft-Versus-Leukemia (GVL) Effect Against B Cell Acute Lymphoblastic Leukemia from Graft-Versus-Host Disease (GVHD) After Hematopoietic Cell Transplant?

• Journal: Frontiers in Pediatrics, March 2022
• Authors: Rozmus J, Bhatt ST, Buxbaum NP, Cuvelier GDE, Li AM, Kitko CL, Schultz KR
• Citation: Front Pediatr. 2022 Mar 24;10:796994. doi: 10.3389/fped.2022.796994.

Immunometabolic Therapeutic Targets of Graft-versus-Host Disease (GvHD)

• Journal: Metabolites, October 2021
• Authors: Mhandire K, Saggu K, Buxbaum NP
• Citation: Metabolites. 2021 Oct 27;11(11):736. doi: 10.3390/metabo11110736.

BAD(FF) to the bone: misbehaving B cells in cGVHD

• Journal: Blood, May 2021
• Authors: Buxbaum NP
• Citation: Blood. 2021 May 6;137(18):2426-2427. doi: 10.1182/blood.2021011008.

Glycolytic metabolism of pathogenic T cells enables early detection of GVHD by ¹³C-MRI

• Journal: Blood, January 2021
• Authors: Assmann JC, Farthing DE, Saito K, Maglakelidze N, Oliver B, Warrick KA, Sourbier C, Ricketts CJ, Meyer TJ, Pavletic SZ, Linehan WM, Krishna MC, Gress RE, Buxbaum NP
• Citation: Blood. 2021 Jan 7;137(1):126-137. doi: 10.1182/blood.2020005770.

Autoimmunity Following Allogeneic Hematopoietic Stem Cell Transplantation

• Journal: Frontiers in Immunology, August 2022
• Authors: Buxbaum NP, Pavletic SZ
• Citation: Front Immunol. 2020 Aug 25;11:2017. doi: 10.3389/fimmu.2020.02017.

We didn't start the fire, MDSC inflammasome signaling in GVHD

• Journal: Blood, November 2019
• Authors: Buxbaum NP
• Citation: Blood. 2019 Nov 7;134(19):1570-1572. doi: 10.1182/blood.2019003247.

In vivo kinetics and nonradioactive imaging of rapidly proliferating cells in graft-versus-host disease

• Journal: JCI Insight, June 2017
• Authors: Buxbaum NP, Farthing DE, Maglakelidze N, Lizak M, Merkle H, Carpenter AC, Oliver BU, Kapoor V, Castro E, Swan GA, Dos Santos LM, Bouladoux NJ, Bare CV, Flomerfelt FA, Eckhaus MA, Telford WG, Belkaid Y, Bosselut RJ, Gress RE
• Citation: JCI Insight. 2017 Jun 15;2(12):e92851. doi: 10.1172/jci.insight.92851.