Research in the laboratory of John Ebos, PhD, focuses on the off-target "host" effects of cancer therapy that can be used as biomarkers to optimize treatment.

Researcher at Roswell Park Comprehensive Cancer Center Receives American Cancer Society Award

  • Dr. Ebos received one of 110 grants nationally totaling more than $47.6 million
  • Award will fund effort to develop better therapies for metastatic kidney cancer
  • Work focuses on vaccine to control tumors that no longer respond to treatment

Editor's note: This press release was first issued by the American Cancer Society and is reproduced here with permission. 

BUFFALO, N.Y. — The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has approved funding for two grants totaling $832,000 to researchers in Upstate New York in the first of two grant cycles for 2018. The grants are among 110 national research and training grants totaling more than $47.6 million that will fund investigators at 72 institutions across the United States in the latest round of funding. The grants go into effect July 1, 2018.

Locally, the American Cancer Society has awarded a $792,000 multi-year research grant to John Ebos, PhD, at Roswell Park Comprehensive Cancer Center.  “The American Cancer Society research grant has changed the momentum of my work, providing financial stability for my lab and allowing me to find answers to questions we have been asking for more than 10 years,” said Dr. Ebos.

Patients with metastatic kidney cancer often stop treatment when the tumor becomes resistant to the drugs they are receiving. In many cases, the tumor can immediately begin to grow again. Dr. Ebos is studying a vaccine to inhibit the tumor growth that often happens when treatment has stopped, providing much-needed time to identify new treatment options for the patient.

Since 1946, the American Cancer Society has funded research and training of health professionals to investigate the causes, prevention, and early detection of cancer, as well as new treatments, cancer survivorship, and end of life support for patients and their families. In those 71 years, the American Cancer Society’s extramural research grants program has devoted more than $4.6 billion to cancer research and is honored to have given funding to 47 investigators who went on to win the Nobel Prize.

The Council for Extramural Research also approved 90 grant applications totaling more than $43.1 million that could not be funded due to budgetary constraints. These “pay-if” applications represent work that passed the Society’s multi-disciplinary review process but are beyond the Society’s current funding resources. They can be and often are subsidized by donors who wish to support research that would not otherwise be funded. In 2017, more than $11.5 million in additional funding helped finance 39 “pay-if” applications.

For more information about the American Cancer Society Research Program, please visit

Media Contact

Annie Deck-Miller, Senior Media Relations Manager