Hope was the driving force behind the new Roswell Park logo, which led us to ask our social media followers what the word means to them. The responses were powerful and, of course, inspired hope.

Exciting new changes are in the works at Roswell Park, just in time for our 120th anniversary!

Epigenetics describes how normal genes that control the body’s functions can be switched on or off by different exposures and experiences, from before birth through adulthood. These changes could potentially affect the health of our offspring for generations.

Holiday cards are meant to bring merry greetings of cheer to friends and family, but what if someone on your list is facing this Christmas with cancer? Will the message of joy and wishes for a happy new year seem trite or even crass to a patient in treatment? A well-intentioned card could send the wrong message.

Cancer can occur when certain normal genes are "switched on or off" as a result of environmental epigenetics — influences that occur throughout your life. Some drugs have already been developed to correct the on/off switch for some types of cancer.

More than a century after his death, the legacy of Dr. Roswell Park remains strong. Today, Nov. 13, 2017, Buffalo Business First will induct him into the inaugural class of the Western New York Business Hall of Fame, which recognizes the region’s preeminent business leaders and innovators from the 1800s to the present. Here’s a brief introduction to this remarkable man.

“Someone may have a really significant exposure over a short period of time or a moderate exposure over a long period of time. What we know about asbestos and diesel and silica is, the greater the dose, the greater the risk.”

Weight management is by far the most personal part of my journey I’ve talked about so far. I can’t tell you how many hours I’ve spent elated or devastated reacting to the numbers on the scale and how they are represented on my body.