2023 MPE Meeting

The 6th International Molecular Pathological Epidemiology (MPE) Meeting: 10-Year Anniversary Summit

The International Molecular Pathological Epidemiology (MPE) Meeting Series is a unique meeting series open to the international research community with free registration. Founded by Shuji Ogino, MD, PhD, in 2013, the International Molecular Pathological Epidemiology (MPE) Meeting Series held its 10-year Anniversary Summit at Roswell Park Comprehensive Cancer Center on May 4-5, 2023. This unique meeting provided an unprecedented opportunity for interdisciplinary collaboration and integration of multiple diverse fields.

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2023 Agenda

Thursday, May 4: Special Forum for Germline & Somatic Genomics and Social and Structural Determinants of Health in Cancer Disparities

7 - 8 a.m. - Breakfast

8 a.m. - Welcome: Shuji Ogino, MD, PhD and Christine Ambrosone, PhD

Plenary Sessions 1 & 2: Self-reported Race and Ethnicity, Genetic Ancestry and Social and Structural Determinants of Health: Where do they Meet in Cancer Disparities? (Chair: Christine Ambrosone, PhD)

8:05 - 9:35 a.m. - Plenary Session 1

Timothy Rebbeck, PhD, Keynote Address: Biological and Social Drivers of Cancer Health Disparities
Salma Shariff-Marco, PhD, MPH: Investigating the Structural and Social Drivers of Cancer Health Disparities
Song Yao, PhD: Tumor Mutations and Risk Factors

9:35 - 9:55 a.m. - Break

9:55 - 11:40 a.m. - Plenary Session 2

Brittany Lord, PhD, MPH, MS: The Impact of Neighborhood Deprivation on DNA Methylation in Breast Cancer
Angela Omilian, PhD: The Role of Self-identified Race and Ethnicity, Neighborhood Socioeconomic Status, and Genetic Ancestry on Breast Cancer Outcomes in the Pathways Study
Ken Batai, PhD: Kidney Cancer Health Disparities: Exploring Role of Social Determinants of Health

11:40 a.m. - Group Photo

12 - 2 p.m. - Lunch and Poster Session

2 - 3:05 p.m. - Chair Session 1: Integration of Genomics and Macro-Microenvironment (Chair: Montse Garcia-Closas, PhD)

Matthew Meyerson, MD, PhD, Keynote Address: Genetic Epidemiology and Microbiology of Human Lung and Colon Cancers
Gretchen Gierach, PhD, MPH: Integrating Macro-Microenivronment Biomarkers of Breast Tissue Composition to Inform Breast Cancer Etiology and Progression

3:05 - 3:25 p.m. - Break

3:25 - 4:40 p.m. - Chair Session 2: Influence of Lifestyle, Behavioral, and Genetic Factors on Tumor and Normal Tissues (Chair: Peter Campbell, PhD)

David Cheng, PhD: mTOR Pathway Signaling: a Mechanistic Link between Energy Imbalance and Breast Cancer
Shelley Tworoger, PhD: Immunologic Predictors of Survival Among Patients with Ovarian Cancer
Maria Teresa Landi, MD, PhD: The Interplay of Exogenous and Endogenous Mutational Processes in Lung Cancer Evolution

4:40 p.m. - Niagara Falls Tour

Friday, May 5th: Future Preview - Spatial Analyses; Bioinformatics; Artificial Intelligence

7 - 8 a.m. - Breakfast

8:15 - 9:35 a.m. - Chair Session 1 (Chair: Shuji Ogino, MD, PhD)

Jonathan Nowak, MD, PhD: Utility of Tissue-based Tumor Microenvironment Profiling in Large Patient Cohorts
Stephanie Schmit, PhD, MPH: Investigating the Epidemiology of T Cell Responses in Colorectal Cancer and Developing Efforts in Diverse Populations
Mustapha Abubakar, MD, PhD: Heterogeneity in Exposure-tissue Interactions Parallels Breast Cancer Etiologic Heterogeneity

9:35 a.m. - Break

10 - 11:20 a.m. - Chair Session 2 (Chair: Song Yao, PhD)

Kun-Hsing Yu, MD, PhD: Artificial Intelligence for Integrative Pathology Evaluation
Jonas Almeida, PhD: Mutation Signatures - Unified Presentations of Array Panel and Sequencing Data for AI Analysis
Tomotaka Ugai, MD, PhD: Integration of Cancer Spectra into Large-scale Population Studies for Precision Oncology

11:20 a.m. - Award presentation & open business meeting

12 p.m. - Lunch

2:30 - 3:45 p.m. - Darwin Martin House Tour