Sheila Sait, PhD

Specialty: Cytogenetics
Assistant Director of Clinical Cytogenetics Laboratory and Research Coordinator
Department of Pathology & Laboratory Medicine

 Request an Appointment
Locations

Roswell Park Main Campus
1-800-ROSWELL (1-800-767-9355)

Research Interests:

  • Chromosomal analysis of solid tumors
  • Leukemia and lymphomas

Biography

I joined the staff of Roswell Park Comprehensive Cancer Center (Roswell Park) in 1988. I earned my doctoral degree in Cancer Genetics at Bangalore University, Bangalore, India (1985). I did postdoctoral fellowships both at Roswell Park Comprehensive Cancer Center and at the Genetics Center of Southwest Biomedical Research Institute, Scottsdale, Arizona.

I have faculty appointments in the Department of Cancer Pathology and Prevention at the State University of New York at Buffalo and at Roswell Park Comprehensive Cancer Center. I hold a Certificate of Qualification to serve as Director of a Clinical Cytogenetics Laboratory in New York State. I have also been a mentor to high school students, college students and pathology residents.

My research interests include leukemia and lymphomas and chromosomal analysis of solid tumors. I am a member of the American Society of Human Genetics and have authored or co-authored over 201 publications, book chapters and abstracts.

Positions

Roswell Park Comprehensive Cancer Center

  • Assistant Professor of Oncology
  • Assistant Director of Clinical Cytogenetics Laboratory and Research Coordinator
  • Department of Pathology & Laboratory Medicine

Background

Education and Training

  • 1985 - PhD - Cancer Genetics, Bangalore University, Bangalore, India

Fellowship

  • Postdoctoral Fellowship - Roswell Park Comprehensive Cancer Center
  • Postdoctoral Fellowship - Genetics Center, Southwest Biomedical Research Institute, Scottsdale, AZ

Board Certification

  • Certificate of Qualification, Clinical Cytogenetics Laboratory Director, New York State

Honors & Awards

  • American Society of Human Genetics

Publications

1. Momen N, Baysal B, Jani Sait S, Tario J, Qian YW. Unusual B-Lymphoid Blastic Crisis as Initial Presentation of Chronic Myeloid Leukemia Imposes Diagnostic Challenges. Case Rep Hematol. June 25; 2022.

2. Przespolewski ER, Baron J, Kashef F, Fu K, Jani Sait SN, Hernandez-Ilizaliturri F, Thompson J. Concomitant Venetoclax and Imatinib for Comanaging Chronic Lymphocytic Leukemia and Chronic Myeloid Leukemia: A Case Report. J. Natl Compr Canc Netw. 21(2):102-107. Feb. 2023

3. Torka P, Groman A, Wong J, Nichols J, Kader A, Mavis C, Anampa-Guzman A, Sait SJ, Block A, Przespolewski E, Mohr A, Lund I, McWhite K, Kostrewa J, DeMarco J, Johnson M, Darrall A, Thomas R, Sundaram S, Ghione P, Hutson A, Hernandez-Ilizaliturri FJ. Carfilzomib combined with rituximab, ifosfamide, carboplatin and etoposide for relapsed or refractory DLBCL. Blood Adv. 7(7):1146-1155. April 11, 2023.

4. Qian YW, Wang E, Jani Sait S, Glenn S. Acute Myeloid Leukemia with LRRFIPI:: FGFR1 Rearrangement and a Complex Karyotype. Cancer Genetics. Volumes 278-279, November 2023, Pages 50-54.

5. Zhao M, Ryall S, Brody SJ, Harris AC, Cabral K, Brownstein C, Kim JC, Smith AC, Dal Cin P, Narayan R, Sikkink K, Schmitt A, Hobbs GS, Fathi AT, Griffin GK, Sait SNJ, Iafrate AJ, Aster JC, Graubert TA, Nardi V, Dubuc A. Integrative cytogenetic and molecular studies unmask “chromosomal mimicry” in hematologic malignancies. Blood Advances Final Version published online 26 February 2025.