First in Human Study of IMGN151 in Recurrent Gynaecological Cancers


Study Number
3867623
Phase
I
Age Group
Adult
Purpose

IIMGN151-1001 is a Phase 1, first in human, open-label dose-escalation, optimization, and expansion study designed to characterize the safety, tolerability, pharmacokinetics (PK), immunogenicity, and preliminary antitumor activity of IMGN151 in adult participants with recurrent endometrial cancer; recurrent, high-grade serous epithelial ovarian, fallopian tube, and primary peritoneal cancers; or recurrent cervical cancers. All participants will be, in the opinion of the investigator, appropriate for nonplatinum single-agent therapy for their next line of therapy.

Full Title

A Phase 1, First-in-Human, Open-Label, DoseEscalation and Expansion Study of IMGN151 (anti-FR-alpha antibody drug conjugate) in Adult Patients with Recurrent Gynaecological Cancers

ClinicalTrials.Gov ID
NCT05527184

To inquire about participating in these studies, call 1-800-ROSWELL (1-800-767-9355) or e-mail askroswell@roswellpark.org.