Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

Study Number

3406923

Phase

III

Age Group

Adult

Principal Investigator

Ajay Gupta

Purpose

This is a multicenter, randomized, open label phase lll trial to assess whether preoperative chemotherapy, as an adjunct to curative-intent surgery, improves the prognosis of high risk DDLPS (dedifferentiated Liposarcoma) and LMS (Leiomyosarcoma) patients as measured by disease free survival.

After confirmation of eligibility criteria, patients will be randomized to either the standard arm or experimental arm.

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Full Title

A Randomized Phase III Study of Neoadjuvant Chemotherapy followed by Surgery
versus Surgery Alone for Patients with High Risk RetroPeritoneal Sarcoma (STRASS 2)

ClinicalTrials.Gov ID

NCT04031677

Get more information and eligibility criteria for this trial at ClinicalTrials.gov

To inquire about participating in these studies, call 1-800-ROSWELL (1-800-767-9355) or e-mail askroswell@roswellpark.org.