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Clinical Trial
A Phase I, Dose Escalation and Dose Expansion, Safety and Tolerability Study of onCARlytics (CF33-CD19), Administered Intravenously or Intratumorally in Combination with Blinatumomab in Adults with Advanced or Metastatic Solid Tumors (OASIS)
… Adults with Advanced or Metastatic Solid Tumors (OASIS) I Fountzilas, Christos This is an open-label, dose escalation …
Clinical Trial
HERTHENA-PanTumor01 (U31402-277): A Phase 2, Multicenter, Multicohort, Open-Label, Proof of Concept Study of Patritumab Deruxtecan (HER3-DXd; U3-1402) in Subjects with Locally Advanced or Metastatic Solid Tumors
… with Locally Advanced or Metastatic Solid Tumors II Fountzilas, Christos This is a proof-of-concept study …
Clinical Trial
A Phase 1, Open-Label, Dose Escalation and Expansion, Multicenter Study of Claudin 18.2 Targeted Chimeric Antigen Receptor T-cells in Subjects with Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or…
… Gastroesophageal Junction (GEJ), Esophageal, or… I Fountzilas, Christos This is a Phase 1, Open-Label, Dose …
Blog Post
Can a commonly prescribed blood pressure drug improve survival for patients with esophageal cancer?
… and radiation in those patients,” says Christos Fountzilas, MD, FACP , Co-Leader of the Gastrointestinal … Early Phase Clinical Trials Program at Roswell Park. Dr. Fountzilas was co-author of an article in the journal Lancet …
News
Roswell Park Study First to Show Two-Drug Combination Selectively Targets p53-Mutant Cancers
… in the United States,” notes study co-author Christos Fountzilas, MD, FACP , Co-Leader of the Gastrointestinal … Recognizing the need for better therapeutic options, Dr. Fountzilas and his colleague, Andrei V. Bakin, PhD , …
Blog Post
Burning questions about soothing acid reflux
… (NIHDDK) 11/28/2022 - 10:01 Esophageal Cancer Q&A with Dr. Fountzilas Gastroesophageal junction cancer: Rick's story …
Blog Post
Roswell Park Researchers Find Glucose Drives Growth of the Most Common Type of Esophageal Cancer
… To Reduce Your Cancer Risk Esophageal Cancer Q&A with Dr. Fountzilas Esophageal Cancer Research & News … A recent study …
Clinical Trial
A Phase I Study of Trifluridine/ Tipiracil plus the Poly (ADP) Ribose Polymerase Inhibitor Talazoparib in Advanced Cancers
… Polymerase Inhibitor Talazoparib in Advanced Cancers I Fountzilas, Christos This phase I trial investigates the side …
Clinical Trial
A Phase 1b/2, Dose-escalation, Randomized, Multi-Center Study of Maintenance Ivaltinostat plus Capecitabine or Capecitabine Monotherapy in Patients with Metastatic Pancreatic Adenocarcinoma whose Disease has not Progressed on First Line FOLFIRINOX…
… Disease has not Progressed on First Line FOLFIRINOX… I Fountzilas, Christos This study is a Phase 1b/2, …
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Bakin Lab Research Focus
… Working with co-author and Roswell Park colleague Christos Fountzilas, MD, FACP , the Bakin Lab investigated DNA repair … ) Roswell Park research funding NCI R37 Merit Award (Dr. Fountzilas, PI) We discovered that p53-mutant cancer cells …