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Clinical Trial
A Phase III, Randomized, Controlled, Global Multicenter Study to Evaluate the Efficacy and Safety of Oral Tinengotinib versus Physician s Choice in Subjects with Fibroblast Growth Factor Receptor (FGFR)-altered, Chemotherapy- and FGFR Inhibitor…
… (FGFR)-altered, Chemotherapy- and FGFR Inhibitor… III Fountzilas, Christos This study is a Phase III, Randomized, …
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Roswell Park Clinical Trials Add Beta Blocker to Arsenal Against Esophageal Cancer
… chemotherapy, and it becomes progressive.” Dr. Christos Fountzilas “Roswell Park is at the forefront of research on … and radiation in those patients,” says Christos Fountzilas, MD, FACP , Co-Leader of the Gastrointestinal … chemotherapy, and it becomes progressive.” Dr. Christos Fountzilas “Roswell Park is at the forefront of research on …
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Roswell Park Study First to Show Two-Drug Combination Selectively Targets p53-Mutant Cancers
… in the United States,” notes study co-author Christos Fountzilas, MD, FACP , Co-Leader of the Gastrointestinal … Recognizing the need for better therapeutic options, Dr. Fountzilas and his colleague, Andrei V. Bakin, PhD , … for selective targeting of p53-mutant cancers,” Dr. Fountzilas adds. “Of note, while PARP inhibitors are approved …
Clinical Trial
HERTHENA-PanTumor01 (U31402-277): A Phase 2, Multicenter, Multicohort, Open-Label, Proof of Concept Study of Patritumab Deruxtecan (HER3-DXd; U3-1402) in Subjects with Locally Advanced or Metastatic Solid Tumors
… with Locally Advanced or Metastatic Solid Tumors II Fountzilas, Christos This is a proof-of-concept study …
Clinical Trial
CA240-0030; A Randomized, Phase 2/3 Study Comparing BMS-986504 Combined with Gemcitabine and Nab-paclitaxel versus Gemcitabine and Nab-paclitaxel in Participants with Untreated Metastatic Pancreatic Ductal Adenocarcinoma Harboring Homozygous MTAP Deletion
… Adenocarcinoma Harboring Homozygous MTAP Deletion II/III Fountzilas, Christos The purpose of this study is to assess …
Clinical Trial
A Phase I Study of Trifluridine/ Tipiracil plus the Poly (ADP) Ribose Polymerase Inhibitor Talazoparib in Advanced Cancers
… Polymerase Inhibitor Talazoparib in Advanced Cancers I Fountzilas, Christos This phase I trial investigates the side …
Clinical Trial
A Phase 2 Clinical Trial of Nalirifox as Neoadjuvant Treatment for Patients with Borderline Resectable Pancreatic Ductal Adenocarcinoma
… Borderline Resectable Pancreatic Ductal Adenocarcinoma II Fountzilas, Christos This phase II trial tests how well …
Clinical Trial
A Phase I/II Study of Complement Inhibition in Pancreatic Ductal Adenocarcinoma
… Inhibition in Pancreatic Ductal Adenocarcinoma I/II Fountzilas, Christos This phase I/II trial tests the effect …
Clinical Trial
A Phase 1 Study of ASP3082 in Participants with Previously Treated Locally Advanced or Metastatic Solid Tumor Malignancies with KRAS G12D Mutation
… Solid Tumor Malignancies with KRAS G12D Mutation I Fountzilas, Christos This is an open-label study. This means …
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Pancreas Advocacy Group Names Roswell Park an Academic Center of Excellence
… every stage of treatment and survivorship,” says Christos Fountzilas, MD , a medical oncologist at Roswell Park. “It’s … every stage of treatment and survivorship,” says Christos Fountzilas, MD , a medical oncologist at Roswell Park. “It’s …