Specializing In:
- Unknown primary cancer
Research Interests:
- Develop novel therapies for rare cancer
- Immunotherapy
- Biomarkers
- Quality of life research
Biography
I am staff medical oncologist overseeing quality, continuing education, recruitment and integration of care between the Roswell Park Care Network and Main Campus. I am passionate about bringing cutting edge and high-quality care to patients wherever they may be and am involved in many efforts to increase our research and supportive care offerings in the care network to improve outcomes. Being involved in many national groups that develop the guidelines and various other national organizations like the NCCN, I am actively involved in learning and shaping the future of cancer care for all cancer patients.
While I do not have an active clinical practice, I am part of many programs that support them and advocating for them wherever I can.
Positions
Roswell Park Comprehensive Cancer Center
- Professor of Oncology
Roswell Park Care Network
- Medical Director, Medical Oncology, Roswell Park Care Network
National Comprehensive Cancer Network
- Chief Medical Officer
Background
Education and Training
- 1998 - MD - Grant Medical College, University of Mumbai, Maharashtra, India
Residency
- 1998-2001 - Resident - Internal Medicine, Lincoln Medical and Mental Health Center and Cornell University School of Medicine, Bronx, NY
Fellowship
- 2004 - Medical Oncology, Roswell Park Cancer Institute, Buffalo, NY
- 1998 - Post Doctoral Fellowship, Fox Chase Cancer Center, Philadelphia, PA
Board Certification
- 2001 - Internal Medicine, American Board of Internal Medicine
- 2003, 2005 - Medical Oncology, American Board of Internal Medicine
Professional Memberships
- Cholangiocarcinoma Foundation
- Cholangiocarcinoma Foundation - Medical Advisory Board
- Cholangiocarcinoma Foundation - Nursing Advisory Board
- NANETs
- NANETs - Regional Conference Committee Chair
- Hepatobiliary Cancer Panel, National Comprehensive Cancer Network
- American Association for Cancer Research
- Carcinoid.org NET Physician/Expert
- American Association for the Study of Liver Diseases
- American College of Gastroenterology
- American College of Surgeons Oncology Group
- American Society of Clinical Oncology
Honors & Awards
- 2021 - Mark R. Clements Award, for Vision Innovation and Collaboration from the Cholangiocarcinoma Foundation
- 2018 - Best Teacher Award, Awarded by Roswell Park Comprehensive Cancer Center Medical Oncology Fellows
- 2008 - Best Teacher Award, Awarded by Roswell Park Comprehensive Cancer Center Medical Oncology Fellows
- 2006 - American Cancer Society Scholar Award
- 2003 - Thomas Frawley Resident Research Fellowship award, by State University of New York at Buffalo
- 2002 - ASCO-AACR Methods in Clinical Cancer Research Workshop Attendee, Vail, CO
- 1997 - Junior Investigator Award, Tenth International Conference on Chemical Modifiers in Cancer Treatment
Research Overview
Research interests in phase 1 and 2 clinical trials in GI cancer and animal models research of liver cancer.
Clinical Trials
Featured on CancerTalk
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Publications
- Kalathil SG, Lugade AA, Miller A, Iyer R, Thanavala Y. PD-1+ and Foxp3+ T cell reduction correlates with survival of HCC patients after sorafenib therapy. JCI Insight. 2016 Jul 21;1(11):e86182. doi: 10.1172/jci.insight.86182. PMID: 27540594; PMCID: PMC4986927.
- Kalathil SG, Lugade AA, Iyer R, Miller A, Thanavala Y. Endothelial progenitor cell number and ERK phosphorylation serve as predictive and prognostic biomarkers in advanced hepatocellular carcinoma patients treated with sorafenib. Oncoimmunology. 2016 Sep 20;5(10):e1226718. doi: 10.1080/2162402X.2016.1226718. PMID: 27853648; PMCID: PMC5087301.
- Kalathil S, Lugade AA, Miller A, Iyer R, Thanavala Y. Higher frequencies of GARP(+)CTLA-4(+)Foxp3(+) T regulatory cells and myeloid-derived suppressor cells in hepatocellular carcinoma patients are associated with impaired T-cell functionality. Cancer Res. 2013 Apr 15;73(8):2435-44. doi: 10.1158/0008-5472.CAN-12-3381. Epub 2013 Feb 19. PMID: 23423978; PMCID: PMC3645275.